Vasconcellos ML - Search Results

1

Efficient synthesis of 16 aromatic Morita-Baylis-Hillman adducts: Biological evaluation on Leishmania amazonensis and Leishmania chagasi.

Junior CG, de Assis PA, Silva FP, Sousa SC, de Andrade NG, Barbosa TP, Nerís PL, Segundo LV, Anjos IC, Carvalho GA, Rocha GB, Oliveira MR, Vasconcellos ML. Junior CG, et al. Among authors: vasconcellos ml. Bioorg Chem. 2010 Dec;38(6):279-84. doi: 10.1016/j.bioorg.2010.08.002. Epub 2010 Sep 19. Bioorg Chem. 2010. PMID: 20855101

2

Improved synthesis of seven aromatic Baylis-Hillman adducts (BHA): evaluation against Artemia salina Leach. and Leishmania chagasi.

Barbosa TP, Junior CG, Silva FP, Lopes HM, Figueiredo LR, Sousa SC, Batista GN, da Silva TG, Silva TM, de Oliveira MR, Vasconcellos ML. Barbosa TP, et al. Among authors: vasconcellos ml. Eur J Med Chem. 2009 Apr;44(4):1726-30. doi: 10.1016/j.ejmech.2008.03.016. Epub 2008 Mar 29. Eur J Med Chem. 2009. PMID: 18448204

3

3-Hydroxy-2-methylene-3-(4-nitrophenylpropanenitrile): A new highly active compound against epimastigote and trypomastigote form of Trypanosoma cruzi.

Sandes JM, Borges AR, Junior CG, Silva FP, Carvalho GA, Rocha GB, Vasconcellos ML, Figueiredo RC. Sandes JM, et al. Among authors: vasconcellos ml. Bioorg Chem. 2010 Oct;38(5):190-5. doi: 10.1016/j.bioorg.2010.06.003. Epub 2010 Jul 1. Bioorg Chem. 2010. PMID: 20638707

4

Design, synthesis and antileishmanial in vitro activity of new series of chalcones-like compounds: a molecular hybridization approach.

Barbosa TP, Sousa SC, Amorim FM, Rodrigues YK, de Assis PA, Caldas JP, Oliveira MR, Vasconcellos ML. Barbosa TP, et al. Among authors: vasconcellos ml. Bioorg Med Chem. 2011 Jul 15;19(14):4250-6. doi: 10.1016/j.bmc.2011.05.055. Epub 2011 Jun 1. Bioorg Med Chem. 2011. PMID: 21684751 Free article.

5

Synthesis, evaluation against Leishmania amazonensis and cytotoxicity assays in macrophages of sixteen new congeners Morita-Baylis-Hillman adducts.

Silva FP, de Assis PA, Junior CG, de Andrade NG, da Cunha SM, Oliveira MR, Vasconcellos ML. Silva FP, et al. Among authors: vasconcellos ml. Eur J Med Chem. 2011 Sep;46(9):4295-301. doi: 10.1016/j.ejmech.2011.06.036. Epub 2011 Jul 5. Eur J Med Chem. 2011. PMID: 21775030

6

Antimitotic activity on sea urchin embryonic cells of seven antiparasitic Morita-Baylis-Hillman adducts: a potential new class of anticancer drugs.

Leite JC, Junior CG, Silva FP, Sousa SC, Vasconcellos ML, Marques-Santos LF. Leite JC, et al. Among authors: vasconcellos ml. Med Chem. 2012 Nov;8(6):1003-11. doi: 10.2174/1573406411208061003. Med Chem. 2012. PMID: 22830498

7

Morita-Baylis-Hillman adduct shows in vitro activity against Leishmania (Viannia) braziliensis associated with a reduction in IL-6 and IL-10 but independent of nitric oxide.

Amorim FM, Rodrigues YK, Barbosa TP, Néris PL, Caldas JP, Sousa SC, Leite JA, Rodrigues-Mascarenhas S, Vasconcellos ML, Oliveira MR. Amorim FM, et al. Among authors: vasconcellos ml. Parasitology. 2013 Jan;140(1):29-38. doi: 10.1017/S0031182012001291. Epub 2012 Aug 20. Parasitology. 2013. PMID: 22906971

8

Morita-Baylis-Hillman adducts: biological activities and potentialities to the discovery of new cheaper drugs.

Lima-Junior CG, Vasconcellos ML. Lima-Junior CG, et al. Among authors: vasconcellos ml. Bioorg Med Chem. 2012 Jul 1;20(13):3954-71. doi: 10.1016/j.bmc.2012.04.061. Epub 2012 May 9. Bioorg Med Chem. 2012. PMID: 22632793

9

Synthesis and activity of novel homodimers of Morita-Baylis-Hillman adducts against Leishmania donovani: A twin drug approach.

da Silva WAV, Rodrigues DC, de Oliveira RG, Mendes RKS, Olegário TR, Rocha JC, Keesen TSL, Lima-Junior CG, Vasconcellos MLAA. da Silva WAV, et al. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4523-4526. doi: 10.1016/j.bmcl.2016.07.022. Epub 2016 Aug 1. Bioorg Med Chem Lett. 2016. PMID: 27520941

10

Morita-Baylis-Hillman adducts derived from thymol: synthesis, in silico studies and biological activity against Giardia lamblia.

Xavier FJS, Lira AB, Verissimo GC, de S Saraiva FS, de Oliveira Filho AA, de Souza-Fagundes EM, de F F M Diniz M, Gomes MA, Castro AC, Silva FPL, Lima-Junior CG, Vasconcellos MLAA. Xavier FJS, et al. Among authors: vasconcellos mlaa. Mol Divers. 2022 Aug;26(4):1969-1982. doi: 10.1007/s11030-021-10308-1. Epub 2021 Sep 5. Mol Divers. 2022. PMID: 34482477

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