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Artemisolide is a typical inhibitor of IkappaB kinase beta targeting cysteine-179 residue and down-regulates NF-kappaB-dependent TNF-alpha expression in LPS-activated macrophages.
Kim BH, Lee JY, Seo JH, Lee HY, Ryu SY, Ahn BW, Lee CK, Hwang BY, Han SB, Kim Y. Kim BH, et al. Among authors: lee ck, lee jy, lee hy. Biochem Biophys Res Commun. 2007 Sep 28;361(3):593-8. doi: 10.1016/j.bbrc.2007.07.069. Epub 2007 Jul 24. Biochem Biophys Res Commun. 2007. PMID: 17669364
Diarctigenin, a lignan constituent from Arctium lappa, down-regulated zymosan-induced transcription of inflammatory genes through suppression of DNA binding ability of nuclear factor-kappaB in macrophages.
Kim BH, Hong SS, Kwon SW, Lee HY, Sung H, Lee IJ, Hwang BY, Song S, Lee CK, Chung D, Ahn B, Nam SY, Han SB, Kim Y. Kim BH, et al. Among authors: lee ck, lee hy, lee ij. J Pharmacol Exp Ther. 2008 Nov;327(2):393-401. doi: 10.1124/jpet.108.140145. Epub 2008 Aug 11. J Pharmacol Exp Ther. 2008. PMID: 18694995
Effects of scoparone on dopamine release in PC12 cells.
Yang YJ, Lee HJ, Lee BK, Lim SC, Lee CK, Lee MK. Yang YJ, et al. Among authors: lee bk, lee ck, lee mk, lee hj. Fitoterapia. 2010 Sep;81(6):497-502. doi: 10.1016/j.fitote.2010.01.003. Epub 2010 Jan 18. Fitoterapia. 2010. PMID: 20080157
3,190 results