Chin L - Search Results

1

Towards patient-based cancer therapeutics.

Cancer Target Discovery and Development Network; Schreiber SL, Shamji AF, Clemons PA, Hon C, Koehler AN, Munoz B, Palmer M, Stern AM, Wagner BK, Powers S, Lowe SW, Guo X, Krasnitz A, Sawey ET, Sordella R, Stein L, Trotman LC, Califano A, Dalla-Favera R, Ferrando A, Iavarone A, Pasqualucci L, Silva J, Stockwell BR, Hahn WC, Chin L, DePinho RA, Boehm JS, Gopal S, Huang A, Root DE, Weir BA, Gerhard DS, Zenklusen JC, Roth MG, White MA, Minna JD, MacMillan JB, Posner BA. Cancer Target Discovery and Development Network, et al. Among authors: chin l. Nat Biotechnol. 2010 Sep;28(9):904-6. doi: 10.1038/nbt0910-904. Nat Biotechnol. 2010. PMID: 20829823 Free PMC article.

2

Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression.

Alland L, Muhle R, Hou H Jr, Potes J, Chin L, Schreiber-Agus N, DePinho RA. Alland L, et al. Among authors: chin l. Nature. 1997 May 1;387(6628):49-55. doi: 10.1038/387049a0. Nature. 1997. PMID: 9139821

3

The INK4a/ARF tumor suppressor: one gene--two products--two pathways.

Chin L, Pomerantz J, DePinho RA. Chin L, et al. Trends Biochem Sci. 1998 Aug;23(8):291-6. doi: 10.1016/s0968-0004(98)01236-5. Trends Biochem Sci. 1998. PMID: 9757829 Review.

4

Malignant melanoma: modern black plague and genetic black box.

Chin L, Merlino G, DePinho RA. Chin L, et al. Genes Dev. 1998 Nov 15;12(22):3467-81. doi: 10.1101/gad.12.22.3467. Genes Dev. 1998. PMID: 9832500 Free article. Review. No abstract available.

5

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis.

Chin L, Artandi SE, Shen Q, Tam A, Lee SL, Gottlieb GJ, Greider CW, DePinho RA. Chin L, et al. Cell. 1999 May 14;97(4):527-38. doi: 10.1016/s0092-8674(00)80762-x. Cell. 1999. PMID: 10338216 Free article.

6

Essential role for oncogenic Ras in tumour maintenance.

Chin L, Tam A, Pomerantz J, Wong M, Holash J, Bardeesy N, Shen Q, O'Hagan R, Pantginis J, Zhou H, Horner JW 2nd, Cordon-Cardo C, Yancopoulos GD, DePinho RA. Chin L, et al. Nature. 1999 Jul 29;400(6743):468-72. doi: 10.1038/22788. Nature. 1999. PMID: 10440378

7

Flipping the oncogene switch: illumination of tumor maintenance and regression.

Chin L, DePinho RA. Chin L, et al. Trends Genet. 2000 Apr;16(4):147-50. doi: 10.1016/s0168-9525(99)01968-x. Trends Genet. 2000. PMID: 10729826 Review.

8

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice.

Artandi SE, Chang S, Lee SL, Alson S, Gottlieb GJ, Chin L, DePinho RA. Artandi SE, et al. Among authors: chin l. Nature. 2000 Aug 10;406(6796):641-5. doi: 10.1038/35020592. Nature. 2000. PMID: 10949306

9

Dual inactivation of RB and p53 pathways in RAS-induced melanomas.

Bardeesy N, Bastian BC, Hezel A, Pinkel D, DePinho RA, Chin L. Bardeesy N, et al. Among authors: chin l. Mol Cell Biol. 2001 Mar;21(6):2144-53. doi: 10.1128/MCB.21.6.2144-2153.2001. Mol Cell Biol. 2001. PMID: 11238948 Free PMC article.

10

Telomere dysfunction alters the chemotherapeutic profile of transformed cells.

Lee KH, Rudolph KL, Ju YJ, Greenberg RA, Cannizzaro L, Chin L, Weiler SR, DePinho RA. Lee KH, et al. Among authors: chin l. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3381-6. doi: 10.1073/pnas.051629198. Proc Natl Acad Sci U S A. 2001. PMID: 11248087 Free PMC article.

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