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Identification of a common Wnt-associated genetic signature across multiple cell types in pulmonary arterial hypertension.
West JD, Austin ED, Gaskill C, Marriott S, Baskir R, Bilousova G, Jean JC, Hemnes AR, Menon S, Bloodworth NC, Fessel JP, Kropski JA, Irwin D, Ware LB, Wheeler L, Hong CC, Meyrick B, Loyd JE, Bowman AB, Ess KC, Klemm DJ, Young PP, Merryman WD, Kotton D, Majka SM. West JD, et al. Among authors: hong cc. Am J Physiol Cell Physiol. 2014 Sep 1;307(5):C415-30. doi: 10.1152/ajpcell.00057.2014. Epub 2014 May 28. Am J Physiol Cell Physiol. 2014. PMID: 24871858 Free PMC article.
The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling.
Shen C, Nayak A, Neitzel LR, Adams AA, Silver-Isenstadt M, Sawyer LM, Benchabane H, Wang H, Bunnag N, Li B, Wynn DT, Yang F, Garcia-Contreras M, Williams CH, Dakshanamurthy S, Hong CC, Ayad NG, Capobianco AJ, Ahmed Y, Lee E, Robbins DJ. Shen C, et al. Among authors: hong cc. Nat Commun. 2021 Sep 6;12(1):5263. doi: 10.1038/s41467-021-25634-z. Nat Commun. 2021. PMID: 34489457 Free PMC article.
The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling.
Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, Li J, D'Souza S, Lebensohn AM, Rohatgi R, Weiss WA, Weiss VL, Williams C, Hong CC, Robbins DJ, Ahmed Y, Lee E. Ng VH, et al. Among authors: hong cc. Nat Commun. 2023 Oct 5;14(1):6173. doi: 10.1038/s41467-023-41836-z. Nat Commun. 2023. PMID: 37798301 Free PMC article.
414 results