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3β-acetyl tormentic acid induces apoptosis of resistant leukemia cells independently of P-gp/ABCB1 activity or expression.
Invest New Drugs. 2012 Feb;30(1):105-13. doi: 10.1007/s10637-010-9524-1. Epub 2010 Sep 4.
Invest New Drugs. 2012.
PMID: 20814731
Natural triterpenoids from Cecropia lyratiloba are cytotoxic to both sensitive and multidrug resistant leukemia cell lines.
Rocha Gda G, Simões M, Lúcio KA, Oliveira RR, Coelho Kaplan MA, Gattass CR.
Rocha Gda G, et al.
Bioorg Med Chem. 2007 Dec 1;15(23):7355-60. doi: 10.1016/j.bmc.2007.07.020. Epub 2007 Aug 22.
Bioorg Med Chem. 2007.
PMID: 17889544
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3β-Acetyl tormentic acid reverts MRP1/ABCC1 mediated cancer resistance through modulation of intracellular levels of GSH and inhibition of GST activity.
Rocha Gda G, Oliveira RR, Kaplan MA, Gattass CR.
Rocha Gda G, et al.
Eur J Pharmacol. 2014 Oct 15;741:140-9. doi: 10.1016/j.ejphar.2014.07.054. Epub 2014 Aug 9.
Eur J Pharmacol. 2014.
PMID: 25111243
Free article.
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Oleanolic acid initiates apoptosis in non-small cell lung cancer cell lines and reduces metastasis of a B16F10 melanoma model in vivo.
Lúcio KA, Rocha Gda G, Monção-Ribeiro LC, Fernandes J, Takiya CM, Gattass CR.
Lúcio KA, et al. Among authors: rocha gda g.
PLoS One. 2011;6(12):e28596. doi: 10.1371/journal.pone.0028596. Epub 2011 Dec 9.
PLoS One. 2011.
PMID: 22174843
Free PMC article.
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Apoptosis-inducing effects of Melissa officinalis L. essential oil in glioblastoma multiforme cells.
Queiroz RM, Takiya CM, Guimarães LP, Rocha Gda G, Alviano DS, Blank AF, Alviano CS, Gattass CR.
Queiroz RM, et al. Among authors: rocha gda g.
Cancer Invest. 2014 Jul;32(6):226-35. doi: 10.3109/07357907.2014.905587. Epub 2014 Apr 18.
Cancer Invest. 2014.
PMID: 24745610
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Pomolic acid induces apoptosis and inhibits multidrug resistance protein MRP1 and migration in glioblastoma cells.
Guimarães LPTP, Rocha GDG, Queiroz RM, Martins CA, Takiya CM, Gattass CR.
Guimarães LPTP, et al.
Oncol Rep. 2017 Oct;38(4):2525-2534. doi: 10.3892/or.2017.5895. Epub 2017 Aug 10.
Oncol Rep. 2017.
PMID: 28849227
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