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G protein-coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice.
Osborn O, Oh DY, McNelis J, Sanchez-Alavez M, Talukdar S, Lu M, Li P, Thiede L, Morinaga H, Kim JJ, Heinrichsdorff J, Nalbandian S, Ofrecio JM, Scadeng M, Schenk S, Hadcock J, Bartfai T, Olefsky JM. Osborn O, et al. Among authors: morinaga h. J Clin Invest. 2012 Jul;122(7):2444-53. doi: 10.1172/JCI61953. Epub 2012 Jun 1. J Clin Invest. 2012. PMID: 22653059 Free PMC article.
FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages.
Fan W, Morinaga H, Kim JJ, Bae E, Spann NJ, Heinz S, Glass CK, Olefsky JM. Fan W, et al. Among authors: morinaga h. EMBO J. 2010 Dec 15;29(24):4223-36. doi: 10.1038/emboj.2010.268. Epub 2010 Nov 2. EMBO J. 2010. PMID: 21045807 Free PMC article.
Neuronal Sirt1 deficiency increases insulin sensitivity in both brain and peripheral tissues.
Lu M, Sarruf DA, Li P, Osborn O, Sanchez-Alavez M, Talukdar S, Chen A, Bandyopadhyay G, Xu J, Morinaga H, Dines K, Watkins S, Kaiyala K, Schwartz MW, Olefsky JM. Lu M, et al. Among authors: morinaga h. J Biol Chem. 2013 Apr 12;288(15):10722-35. doi: 10.1074/jbc.M112.443606. Epub 2013 Mar 1. J Biol Chem. 2013. PMID: 23457303 Free PMC article.
Free fatty acids induce Lhb mRNA but suppress Fshb mRNA in pituitary LβT2 gonadotropes and diet-induced obesity reduces FSH levels in male mice and disrupts the proestrous LH/FSH surge in female mice.
Sharma S, Morinaga H, Hwang V, Fan W, Fernandez MO, Varki N, Olefsky JM, Webster NJ. Sharma S, et al. Among authors: morinaga h. Endocrinology. 2013 Jun;154(6):2188-99. doi: 10.1210/en.2012-2218. Epub 2013 Mar 22. Endocrinology. 2013. PMID: 23525221 Free PMC article.
Characterization of distinct subpopulations of hepatic macrophages in HFD/obese mice.
Morinaga H, Mayoral R, Heinrichsdorff J, Osborn O, Franck N, Hah N, Walenta E, Bandyopadhyay G, Pessentheiner AR, Chi TJ, Chung H, Bogner-Strauss JG, Evans RM, Olefsky JM, Oh DY. Morinaga H, et al. Diabetes. 2015 Apr;64(4):1120-30. doi: 10.2337/db14-1238. Epub 2014 Oct 14. Diabetes. 2015. PMID: 25315009 Free PMC article.
193 results