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Activation of liver X receptor suppresses the production of the IL-12 family of cytokines by blocking nuclear translocation of NF-κBp50.
Canavan M, McCarthy C, Larbi NB, Dowling JK, Collins L, O'Sullivan F, Hurley G, Murphy C, Quinlan A, Moloney G, Darby T, MacSharry J, Kagechika H, Moynagh P, Melgar S, Loscher CE. Canavan M, et al. Innate Immun. 2014 Oct;20(7):675-87. doi: 10.1177/1753425913501915. Epub 2013 Sep 17. Innate Immun. 2014. PMID: 24045337 Free article.
Shining a light on intestinal traffic.
Murphy CT, Nally K, Shanahan F, Melgar S. Murphy CT, et al. Clin Dev Immunol. 2012;2012:808157. doi: 10.1155/2012/808157. Epub 2011 Nov 22. Clin Dev Immunol. 2012. PMID: 22162719 Free PMC article. Review.
TL1A/TNFSF15 directly induces proinflammatory cytokines, including TNFα, from CD3+CD161+ T cells to exacerbate gut inflammation.
Jin S, Chin J, Seeber S, Niewoehner J, Weiser B, Beaucamp N, Woods J, Murphy C, Fanning A, Shanahan F, Nally K, Kajekar R, Salas A, Planell N, Lozano J, Panes J, Parmar H, DeMartino J, Narula S, Thomas-Karyat DA. Jin S, et al. Mucosal Immunol. 2013 Sep;6(5):886-99. doi: 10.1038/mi.2012.124. Epub 2012 Dec 19. Mucosal Immunol. 2013. PMID: 23250276 Free article.
An antitumorigenic role for the IL-33 receptor, ST2L, in colon cancer.
O'Donnell C, Mahmoud A, Keane J, Murphy C, White D, Carey S, O'Riordain M, Bennett MW, Brint E, Houston A. O'Donnell C, et al. Br J Cancer. 2016 Jan 12;114(1):37-43. doi: 10.1038/bjc.2015.433. Epub 2015 Dec 17. Br J Cancer. 2016. PMID: 26679377 Free PMC article.
170 results