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Scientific review and recommendations on preclinical cardiovascular safety evaluation of biologics.
Vargas HM, Bass AS, Breidenbach A, Feldman HS, Gintant GA, Harmer AR, Heath B, Hoffmann P, Lagrutta A, Leishman D, McMahon N, Mittelstadt S, Polonchuk L, Pugsley MK, Salata JJ, Valentin JP. Vargas HM, et al. Among authors: breidenbach a. J Pharmacol Toxicol Methods. 2008 Sep-Oct;58(2):72-6. doi: 10.1016/j.vascn.2008.04.001. Epub 2008 Apr 18. J Pharmacol Toxicol Methods. 2008. PMID: 18508287
Absence of central nervous system and hypothermic effects after single oral administration of high doses of oseltamivir in the rat.
Freichel C, Breidenbach A, Hoffmann G, Körner A, Gatti S, Donner B, Bansod S, Bellot M, Gand L, Weiser T, Singer T, Prinssen EP. Freichel C, et al. Among authors: breidenbach a. Basic Clin Pharmacol Toxicol. 2012 Jul;111(1):50-7. doi: 10.1111/j.1742-7843.2012.00861.x. Epub 2012 Mar 8. Basic Clin Pharmacol Toxicol. 2012. PMID: 22309322 Free article.
Computational toxicology in drug development.
Muster W, Breidenbach A, Fischer H, Kirchner S, Müller L, Pähler A. Muster W, et al. Among authors: breidenbach a. Drug Discov Today. 2008 Apr;13(7-8):303-10. doi: 10.1016/j.drudis.2007.12.007. Epub 2008 Feb 20. Drug Discov Today. 2008. PMID: 18405842 Review.
International Life Sciences Institute (Health and Environmental Sciences Institute, HESI) initiative on moving towards better predictors of drug-induced torsades de pointes.
Bass AS, Darpo B, Breidenbach A, Bruse K, Feldman HS, Garnes D, Hammond T, Haverkamp W, January C, Koerner J, Lawrence C, Leishman D, Roden D, Valentin JP, Vos MA, Zhou YY, Karluss T, Sager P. Bass AS, et al. Among authors: breidenbach a. Br J Pharmacol. 2008 Aug;154(7):1491-501. doi: 10.1038/bjp.2008.279. Br J Pharmacol. 2008. PMID: 18663380 Free PMC article.
44 results