Steffen J - Search Results

1

Immunoproteasomes preserve protein homeostasis upon interferon-induced oxidative stress.

Seifert U, Bialy LP, Ebstein F, Bech-Otschir D, Voigt A, Schröter F, Prozorovski T, Lange N, Steffen J, Rieger M, Kuckelkorn U, Aktas O, Kloetzel PM, Krüger E. Seifert U, et al. Among authors: steffen j. Cell. 2010 Aug 20;142(4):613-24. doi: 10.1016/j.cell.2010.07.036. Cell. 2010. PMID: 20723761 Free article.

2

Proteasomal degradation is transcriptionally controlled by TCF11 via an ERAD-dependent feedback loop.

Steffen J, Seeger M, Koch A, Krüger E. Steffen J, et al. Mol Cell. 2010 Oct 8;40(1):147-58. doi: 10.1016/j.molcel.2010.09.012. Mol Cell. 2010. PMID: 20932482 Free article.

3

TCF11 at the crossroads of oxidative stress and the ubiquitin proteasome system.

Koch A, Steffen J, Krüger E. Koch A, et al. Among authors: steffen j. Cell Cycle. 2011 Apr 15;10(8):1200-7. doi: 10.4161/cc.10.8.15327. Epub 2011 Apr 15. Cell Cycle. 2011. PMID: 21412055

4

The proteasome maturation protein POMP facilitates major steps of 20S proteasome formation at the endoplasmic reticulum.

Fricke B, Heink S, Steffen J, Kloetzel PM, Krüger E. Fricke B, et al. Among authors: steffen j. EMBO Rep. 2007 Dec;8(12):1170-5. doi: 10.1038/sj.embor.7401091. Epub 2007 Oct 19. EMBO Rep. 2007. PMID: 17948026 Free PMC article.

5

Rapid degradation of mutant SLC25A46 by the ubiquitin-proteasome system results in MFN1/2-mediated hyperfusion of mitochondria.

Steffen J, Vashisht AA, Wan J, Jen JC, Claypool SM, Wohlschlegel JA, Koehler CM. Steffen J, et al. Mol Biol Cell. 2017 Mar 1;28(5):600-612. doi: 10.1091/mbc.E16-07-0545. Epub 2017 Jan 5. Mol Biol Cell. 2017. PMID: 28057766 Free PMC article.

6

The great escape: Mgr2 of the mitochondrial TIM23 translocon is a gatekeeper Tasked with releasing membrane proteins.

Steffen J, Koehler CM. Steffen J, et al. Mol Cell. 2014 Dec 4;56(5):613-4. doi: 10.1016/j.molcel.2014.11.022. Mol Cell. 2014. PMID: 25479635 Free article.

7

ER-mitochondria contacts: Actin dynamics at the ER control mitochondrial fission via calcium release.

Steffen J, Koehler CM. Steffen J, et al. J Cell Biol. 2018 Jan 2;217(1):15-17. doi: 10.1083/jcb.201711075. Epub 2017 Dec 19. J Cell Biol. 2018. PMID: 29259094 Free PMC article.

8

Loss of function of SLC25A46 causes lethal congenital pontocerebellar hypoplasia.

Wan J, Steffen J, Yourshaw M, Mamsa H, Andersen E, Rudnik-Schöneborn S, Pope K, Howell KB, McLean CA, Kornberg AJ, Joseph J, Lockhart PJ, Zerres K, Ryan MM, Nelson SF, Koehler CM, Jen JC. Wan J, et al. Among authors: steffen j. Brain. 2016 Nov 1;139(11):2877-2890. doi: 10.1093/brain/aww212. Brain. 2016. PMID: 27543974 Free PMC article.

9

Stendomycin selectively inhibits TIM23-dependent mitochondrial protein import.

Filipuzzi I, Steffen J, Germain M, Goepfert L, Conti MA, Potting C, Cerino R, Pfeifer M, Krastel P, Hoepfner D, Bastien J, Koehler CM, Helliwell SB. Filipuzzi I, et al. Among authors: steffen j. Nat Chem Biol. 2017 Dec;13(12):1239-1244. doi: 10.1038/nchembio.2493. Epub 2017 Oct 9. Nat Chem Biol. 2017. PMID: 28991239 Free PMC article.

10

Pharmacologic rescue of an enzyme-trafficking defect in primary hyperoxaluria 1.

Miyata N, Steffen J, Johnson ME, Fargue S, Danpure CJ, Koehler CM. Miyata N, et al. Among authors: steffen j. Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14406-11. doi: 10.1073/pnas.1408401111. Epub 2014 Sep 18. Proc Natl Acad Sci U S A. 2014. PMID: 25237136 Free PMC article.

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