Hadwiger P - Search Results

1

Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma.

Inda MM, Bonavia R, Mukasa A, Narita Y, Sah DW, Vandenberg S, Brennan C, Johns TG, Bachoo R, Hadwiger P, Tan P, Depinho RA, Cavenee W, Furnari F. Inda MM, et al. Among authors: hadwiger p. Genes Dev. 2010 Aug 15;24(16):1731-45. doi: 10.1101/gad.1890510. Genes Dev. 2010. PMID: 20713517 Free PMC article.

2

EGFRvIII promotes glioma angiogenesis and growth through the NF-κB, interleukin-8 pathway.

Bonavia R, Inda MM, Vandenberg S, Cheng SY, Nagane M, Hadwiger P, Tan P, Sah DW, Cavenee WK, Furnari FB. Bonavia R, et al. Among authors: hadwiger p. Oncogene. 2012 Sep 6;31(36):4054-66. doi: 10.1038/onc.2011.563. Epub 2011 Dec 5. Oncogene. 2012. PMID: 22139077 Free PMC article.

3

FAPP2 gene downregulation increases tumor cell sensitivity to Fas-induced apoptosis.

Tritz R, Hickey MJ, Lin AH, Hadwiger P, Sah DW, Neuwelt EA, Mueller BM, Kruse CA. Tritz R, et al. Among authors: hadwiger p. Biochem Biophys Res Commun. 2009 May 29;383(2):167-71. doi: 10.1016/j.bbrc.2009.03.126. Epub 2009 Mar 31. Biochem Biophys Res Commun. 2009. PMID: 19341712 Free PMC article.

4

siRNA Down-regulation of the PATZ1 Gene in Human Glioma Cells Increases Their Sensitivity to Apoptotic Stimuli.

Tritz R, Mueller BM, Hickey MJ, Lin AH, Gomez GG, Hadwiger P, Sah DW, Muldoon L, Neuwelt EA, Kruse CA. Tritz R, et al. Among authors: hadwiger p. Cancer Ther. 2008;6(B):865-876. Cancer Ther. 2008. PMID: 19081762 Free PMC article.

5

siRNA knock-down of mutant torsinA restores processing through secretory pathway in DYT1 dystonia cells.

Hewett JW, Nery FC, Niland B, Ge P, Tan P, Hadwiger P, Tannous BA, Sah DW, Breakefield XO. Hewett JW, et al. Among authors: hadwiger p. Hum Mol Genet. 2008 May 15;17(10):1436-45. doi: 10.1093/hmg/ddn032. Epub 2008 Feb 7. Hum Mol Genet. 2008. PMID: 18258738 Free PMC article.

6

Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates.

Frank-Kamenetsky M, Grefhorst A, Anderson NN, Racie TS, Bramlage B, Akinc A, Butler D, Charisse K, Dorkin R, Fan Y, Gamba-Vitalo C, Hadwiger P, Jayaraman M, John M, Jayaprakash KN, Maier M, Nechev L, Rajeev KG, Read T, Röhl I, Soutschek J, Tan P, Wong J, Wang G, Zimmermann T, de Fougerolles A, Vornlocher HP, Langer R, Anderson DG, Manoharan M, Koteliansky V, Horton JD, Fitzgerald K. Frank-Kamenetsky M, et al. Among authors: hadwiger p. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11915-20. doi: 10.1073/pnas.0805434105. Epub 2008 Aug 11. Proc Natl Acad Sci U S A. 2008. PMID: 18695239 Free PMC article.

7

Modulation of thermal stability can enhance the potency of siRNA.

Addepalli H, Meena, Peng CG, Wang G, Fan Y, Charisse K, Jayaprakash KN, Rajeev KG, Pandey RK, Lavine G, Zhang L, Jahn-Hofmann K, Hadwiger P, Manoharan M, Maier MA. Addepalli H, et al. Among authors: hadwiger p. Nucleic Acids Res. 2010 Nov;38(20):7320-31. doi: 10.1093/nar/gkq568. Epub 2010 Jul 7. Nucleic Acids Res. 2010. PMID: 20610434 Free PMC article.

8

Gene silencing by RNAi in mammalian cells.

John M, Geick A, Hadwiger P, Vornlocher HP, Heidenreich O. John M, et al. Among authors: hadwiger p. Curr Protoc Mol Biol. 2003 May;Chapter 26:Unit 26.2. doi: 10.1002/0471142727.mb2602s62. Curr Protoc Mol Biol. 2003. PMID: 18265326

9

Selective inhibition of FLICE-like inhibitory protein expression with small interfering RNA oligonucleotides is sufficient to sensitize tumor cells for TRAIL-induced apoptosis.

Siegmund D, Hadwiger P, Pfizenmaier K, Vornlocher HP, Wajant H. Siegmund D, et al. Among authors: hadwiger p. Mol Med. 2002 Nov;8(11):725-32. Mol Med. 2002. PMID: 12520089 Free PMC article.

10

Small interfering RNA targeting bcl-2 sensitizes malignant melanoma.

Wacheck V, Losert D, Günsberg P, Vornlocher HP, Hadwiger P, Geick A, Pehamberger H, Müller M, Jansen B. Wacheck V, et al. Among authors: hadwiger p. Oligonucleotides. 2003;13(5):393-400. doi: 10.1089/154545703322617078. Oligonucleotides. 2003. PMID: 15000830

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