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Deconvolution of complex G protein-coupled receptor signaling in live cells using dynamic mass redistribution measurements.
Nat Biotechnol. 2010 Sep;28(9):943-9. doi: 10.1038/nbt.1671. Epub 2010 Aug 15.
Nat Biotechnol. 2010.
PMID: 20711173
Free article.
An optical dynamic mass redistribution assay reveals biased signaling of dualsteric GPCR activators.
Kebig A, Kostenis E, Mohr K, Mohr-Andrä M.
Kebig A, et al.
J Recept Signal Transduct Res. 2009;29(3-4):140-5. doi: 10.1080/10799890903047437.
J Recept Signal Transduct Res. 2009.
PMID: 19586284
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Dualsteric GPCR targeting: a novel route to binding and signaling pathway selectivity.
Antony J, Kellershohn K, Mohr-Andrä M, Kebig A, Prilla S, Muth M, Heller E, Disingrini T, Dallanoce C, Bertoni S, Schrobang J, Tränkle C, Kostenis E, Christopoulos A, Höltje HD, Barocelli E, De Amici M, Holzgrabe U, Mohr K.
Antony J, et al. Among authors: kebig a.
FASEB J. 2009 Feb;23(2):442-50. doi: 10.1096/fj.08-114751. Epub 2008 Oct 8.
FASEB J. 2009.
PMID: 18842964
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The allosteric vestibule of a seven transmembrane helical receptor controls G-protein coupling.
Bock A, Merten N, Schrage R, Dallanoce C, Bätz J, Klöckner J, Schmitz J, Matera C, Simon K, Kebig A, Peters L, Müller A, Schrobang-Ley J, Tränkle C, Hoffmann C, De Amici M, Holzgrabe U, Kostenis E, Mohr K.
Bock A, et al. Among authors: kebig a.
Nat Commun. 2012;3:1044. doi: 10.1038/ncomms2028.
Nat Commun. 2012.
PMID: 22948826
Free PMC article.
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Allosteric small molecules unveil a role of an extracellular E2/transmembrane helix 7 junction for G protein-coupled receptor activation.
Jäger D, Schmalenbach C, Prilla S, Schrobang J, Kebig A, Sennwitz M, Heller E, Tränkle C, Holzgrabe U, Höltje HD, Mohr K.
Jäger D, et al. Among authors: kebig a.
J Biol Chem. 2007 Nov 30;282(48):34968-76. doi: 10.1074/jbc.M705563200. Epub 2007 Sep 21.
J Biol Chem. 2007.
PMID: 17890226
Free article.
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[Cinacalcet - an allosteric enhancer at the Ca2+-receptor].
Kebig A, Mohr K.
Kebig A, et al.
Dtsch Med Wochenschr. 2008 Aug;133(33):1681-3. doi: 10.1055/s-0028-1082785. Epub 2008 Jul 25.
Dtsch Med Wochenschr. 2008.
PMID: 18661462
Review.
German.
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[Angiogenesis inhibitors in cancer therapy. Bevacizumab against colon carcinoma].
Fieth C, Kebig A, Mohr K.
Fieth C, et al. Among authors: kebig a.
Pharm Unserer Zeit. 2007;36(6):442-5. doi: 10.1002/pauz.200700240.
Pharm Unserer Zeit. 2007.
PMID: 17957688
Review.
German.
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