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Inhibition of the soluble epoxide hydrolase by tyrosine nitration.
Barbosa-Sicard E, Frömel T, Keserü B, Brandes RP, Morisseau C, Hammock BD, Braun T, Krüger M, Fleming I. Barbosa-Sicard E, et al. J Biol Chem. 2009 Oct 9;284(41):28156-28163. doi: 10.1074/jbc.M109.054759. Epub 2009 Aug 24. J Biol Chem. 2009. PMID: 19704161 Free PMC article.
Soluble epoxide hydrolase deficiency attenuates neointima formation in the femoral cuff model of hyperlipidemic mice.
Revermann M, Schloss M, Barbosa-Sicard E, Mieth A, Liebner S, Morisseau C, Geisslinger G, Schermuly RT, Fleming I, Hammock BD, Brandes RP. Revermann M, et al. Among authors: barbosa sicard e. Arterioscler Thromb Vasc Biol. 2010 May;30(5):909-14. doi: 10.1161/ATVBAHA.110.204099. Epub 2010 Mar 11. Arterioscler Thromb Vasc Biol. 2010. PMID: 20224052 Free PMC article.
Cytochrome P450 epoxygenase gene function in hypoxic pulmonary vasoconstriction and pulmonary vascular remodeling.
Pokreisz P, Fleming I, Kiss L, Barbosa-Sicard E, Fisslthaler B, Falck JR, Hammock BD, Kim IH, Szelid Z, Vermeersch P, Gillijns H, Pellens M, Grimminger F, van Zonneveld AJ, Collen D, Busse R, Janssens S. Pokreisz P, et al. Hypertension. 2006 Apr;47(4):762-70. doi: 10.1161/01.HYP.0000208299.62535.58. Epub 2006 Feb 27. Hypertension. 2006. PMID: 16505204 Free PMC article.
Complementary screening techniques yielded fragments that inhibit the phosphatase activity of soluble epoxide hydrolase.
Hahn S, Achenbach J, Buscató E, Klingler FM, Schroeder M, Meirer K, Hieke M, Heering J, Barbosa-Sicard E, Loehr F, Fleming I, Doetsch V, Schubert-Zsilavecz M, Steinhilber D, Proschak E. Hahn S, et al. Among authors: barbosa sicard e. ChemMedChem. 2011 Dec 9;6(12):2146-9. doi: 10.1002/cmdc.201100433. Epub 2011 Oct 21. ChemMedChem. 2011. PMID: 22021219 No abstract available.
23 results