Knaus E - Search Results

1

Acyclic triaryl olefins possessing a sulfohydroxamic acid pharmacophore: synthesis, nitric oxide/nitroxyl release, cyclooxygenase inhibition, and anti-inflammatory studies.

Huang Z, Velázquez C, Abdellatif K, Chowdhury M, Jain S, Reisz J, Dumond J, King SB, Knaus E. Huang Z, et al. Among authors: knaus e. Org Biomol Chem. 2010 Sep 21;8(18):4124-30. doi: 10.1039/c005066k. Epub 2010 Jul 22. Org Biomol Chem. 2010. PMID: 20664853

2

Syntheses, calcium channel agonist-antagonist modulation activities, and nitric oxide release studies of nitrooxyalkyl 1,4-dihydro-2,6-dimethyl-3-nitro-4-(2,1,3-benzoxadiazol-4-yl)pyridine-5-carboxylate racemates, enantiomers, and diastereomers.

Shan R, Velazquez C, Knaus EE. Shan R, et al. Among authors: knaus ee. J Med Chem. 2004 Jan 1;47(1):254-61. doi: 10.1021/jm030333h. J Med Chem. 2004. PMID: 14695839

3

Synthesis and biological evaluation of 3,4-diphenyl-1,2,5-oxadiazole-2-oxides and 3,4-diphenyl-1,2,5-oxadiazoles as potential hybrid COX-2 inhibitor/nitric oxide donor agents.

Velázquez C, Rao PN, McDonald R, Knaus EE. Velázquez C, et al. Among authors: knaus ee. Bioorg Med Chem. 2005 Apr 15;13(8):2749-57. doi: 10.1016/j.bmc.2005.02.034. Bioorg Med Chem. 2005. PMID: 15781386

4

Novel nonsteroidal antiinflammatory drugs possessing a nitric oxide donor diazen-1-ium-1,2-diolate moiety: design, synthesis, biological evaluation, and nitric oxide release studies.

Velázquez C, Praveen Rao PN, Knaus EE. Velázquez C, et al. Among authors: knaus ee. J Med Chem. 2005 Jun 16;48(12):4061-7. doi: 10.1021/jm050211k. J Med Chem. 2005. PMID: 15943479

5

Novel (E)-2-(aryl)-3-(4-methanesulfonylphenyl)acrylic ester prodrugs possessing a diazen-1-ium-1,2-diolate moiety: design, synthesis, cyclooxygenase inhibition, and nitric oxide release studies.

Abdellatif KR, Dong Y, Chen QH, Chowdhury MA, Knaus EE. Abdellatif KR, et al. Among authors: knaus ee. Bioorg Med Chem. 2007 Nov 1;15(21):6796-801. doi: 10.1016/j.bmc.2007.07.021. Epub 2007 Aug 22. Bioorg Med Chem. 2007. PMID: 17764958

6

Synthesis and cyclooxygenase inhibitory activities of linear 1-(methanesulfonylphenyl or benzenesulfonamido)-2-(pyridyl)acetylene regioisomers.

Chowdhury MA, Dong Y, Chen QH, Abdellatif KR, Knaus EE. Chowdhury MA, et al. Among authors: knaus ee. Bioorg Med Chem. 2008 Feb 15;16(4):1948-56. doi: 10.1016/j.bmc.2007.11.003. Epub 2007 Nov 5. Bioorg Med Chem. 2008. PMID: 18023187

7

Diazen-1-ium-1,2-diolated and nitrooxyethyl nitric oxide donor ester prodrugs of anti-inflammatory (E)-2-(aryl)-3-(4-methanesulfonylphenyl)acrylic acids: synthesis, cyclooxygenase inhibition, and nitric oxide release studies.

Abdellatif KR, Chowdhury MA, Dong Y, Chen QH, Knaus EE. Abdellatif KR, et al. Among authors: knaus ee. Bioorg Med Chem. 2008 Mar 15;16(6):3302-8. doi: 10.1016/j.bmc.2007.12.006. Epub 2007 Dec 8. Bioorg Med Chem. 2008. PMID: 18096394

8

Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 1-(4-methanesulfonylphenyl)-5-aryl-1H-pyrazol-3-carboxylic acids: synthesis, nitric oxide release studies and anti-inflammatory activities.

Abdellatif KR, Chowdhury MA, Dong Y, Knaus EE. Abdellatif KR, et al. Among authors: knaus ee. Bioorg Med Chem. 2008 Jul 1;16(13):6528-34. doi: 10.1016/j.bmc.2008.05.028. Epub 2008 May 17. Bioorg Med Chem. 2008. PMID: 18513975

9

Synthesis of new 4-[2-(4-methyl(amino)sulfonylphenyl)-5-trifluoromethyl-2H-pyrazol-3-yl]-1,2,3,6-tetrahydropyridines: a search for novel nitric oxide donor anti-inflammatory agents.

Chowdhury MA, Abdellatif KR, Dong Y, Knaus EE. Chowdhury MA, et al. Among authors: knaus ee. Bioorg Med Chem. 2008 Oct 1;16(19):8882-8. doi: 10.1016/j.bmc.2008.08.059. Epub 2008 Aug 29. Bioorg Med Chem. 2008. PMID: 18789699

10

Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-hydroxymethylphenyl)-1-(4-aminosulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its methanesulfonyl analog: synthesis, biological evaluation and nitric oxide release studies.

Abdellatif KR, Chowdhury MA, Dong Y, Velázquez C, Das D, Suresh MR, Knaus EE. Abdellatif KR, et al. Among authors: knaus ee. Bioorg Med Chem. 2008 Nov 15;16(22):9694-8. doi: 10.1016/j.bmc.2008.10.001. Epub 2008 Oct 5. Bioorg Med Chem. 2008. PMID: 18930406

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