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Select α-arrestins control cell-surface abundance of the mammalian Kir2.1 potassium channel in a yeast model.
Hager NA, Krasowski CJ, Mackie TD, Kolb AR, Needham PG, Augustine AA, Dempsey A, Szent-Gyorgyi C, Bruchez MP, Bain DJ, Kwiatkowski AV, O'Donnell AF, Brodsky JL. Hager NA, et al. Among authors: mackie td. J Biol Chem. 2018 Jul 13;293(28):11006-11021. doi: 10.1074/jbc.RA117.001293. Epub 2018 May 21. J Biol Chem. 2018. PMID: 29784874 Free PMC article.
Linking chanelopathies with endoplasmic reticulum associated degradation.
O'Donnell BM, Mackie TD, Brodsky JL. O'Donnell BM, et al. Among authors: mackie td. Channels (Austin). 2017 Nov 2;11(6):499-501. doi: 10.1080/19336950.2017.1357944. Epub 2017 Aug 18. Channels (Austin). 2017. PMID: 28723237 Free PMC article. No abstract available.
Transmembrane helix hydrophobicity is an energetic barrier during the retrotranslocation of integral membrane ERAD substrates.
Guerriero CJ, Reutter KR, Augustine AA, Preston GM, Weiberth KF, Mackie TD, Cleveland-Rubeor HC, Bethel NP, Callenberg KM, Nakatsukasa K, Grabe M, Brodsky JL. Guerriero CJ, et al. Among authors: mackie td. Mol Biol Cell. 2017 Jul 15;28(15):2076-2090. doi: 10.1091/mbc.E17-03-0184. Epub 2017 May 24. Mol Biol Cell. 2017. PMID: 28539401 Free PMC article.