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Although IL-6 trans-signaling is sufficient to drive local immune responses, classical IL-6 signaling is obligate for the induction of T cell-mediated autoimmunity.
Lissilaa R, Buatois V, Magistrelli G, Williams AS, Jones GW, Herren S, Shang L, Malinge P, Guilhot F, Chatel L, Hatterer E, Jones SA, Kosco-Vilbois MH, Ferlin WG. Lissilaa R, et al. Among authors: kosco vilbois mh. J Immunol. 2010 Nov 1;185(9):5512-21. doi: 10.4049/jimmunol.1002015. Epub 2010 Sep 24. J Immunol. 2010. PMID: 20870936
Selective antibody intervention of Toll-like receptor 4 activation through Fc γ receptor tethering.
Shang L, Daubeuf B, Triantafilou M, Olden R, Dépis F, Raby AC, Herren S, Dos Santos A, Malinge P, Dunn-Siegrist I, Benmkaddem S, Geinoz A, Magistrelli G, Rousseau F, Buatois V, Salgado-Pires S, Reith W, Monteiro R, Pugin J, Leger O, Ferlin W, Kosco-Vilbois M, Triantafilou K, Elson G. Shang L, et al. J Biol Chem. 2014 May 30;289(22):15309-18. doi: 10.1074/jbc.M113.537936. Epub 2014 Apr 15. J Biol Chem. 2014. PMID: 24737331 Free PMC article.
Antibody Neutralization of CXCL10 in Vivo Is Dependent on Binding to Free and Not Endothelial-bound Chemokine: IMPLICATIONS FOR THE DESIGN OF A NEW GENERATION OF ANTI-CHEMOKINE THERAPEUTIC ANTIBODIES.
Bonvin P, Gueneau F, Buatois V, Charreton-Galby M, Lasch S, Messmer M, Christen U, Luster AD, Johnson Z, Ferlin W, Kosco-Vilbois M, Proudfoot A, Fischer N. Bonvin P, et al. J Biol Chem. 2017 Mar 10;292(10):4185-4197. doi: 10.1074/jbc.M116.745877. Epub 2017 Jan 30. J Biol Chem. 2017. PMID: 28154179 Free PMC article.
107 results