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PDGF-CC blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets.
Hou X, Kumar A, Lee C, Wang B, Arjunan P, Dong L, Maminishkis A, Tang Z, Li Y, Zhang F, Zhang SZ, Wardega P, Chakrabarty S, Liu B, Wu Z, Colosi P, Fariss RN, Lennartsson J, Nussenblatt R, Gutkind JS, Cao Y, Li X. Hou X, et al. Among authors: colosi p. Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12216-21. doi: 10.1073/pnas.1004143107. Epub 2010 Jun 21. Proc Natl Acad Sci U S A. 2010. PMID: 20566880 Free PMC article.
Platelet-derived growth factor-DD targeting arrests pathological angiogenesis by modulating glycogen synthase kinase-3beta phosphorylation.
Kumar A, Hou X, Lee C, Li Y, Maminishkis A, Tang Z, Zhang F, Langer HF, Arjunan P, Dong L, Wu Z, Zhu LY, Wang L, Min W, Colosi P, Chavakis T, Li X. Kumar A, et al. Among authors: colosi p. J Biol Chem. 2010 May 14;285(20):15500-15510. doi: 10.1074/jbc.M110.113787. Epub 2010 Mar 15. J Biol Chem. 2010. PMID: 20231273 Free PMC article.
Effect of genome size on AAV vector packaging.
Wu Z, Yang H, Colosi P. Wu Z, et al. Among authors: colosi p. Mol Ther. 2010 Jan;18(1):80-6. doi: 10.1038/mt.2009.255. Epub 2009 Nov 10. Mol Ther. 2010. PMID: 19904234 Free PMC article.
Diabetes enhances the efficacy of AAV2 vectors in the retina: therapeutic effect of AAV2 encoding vasoinhibin and soluble VEGF receptor 1.
Díaz-Lezama N, Wu Z, Adán-Castro E, Arnold E, Vázquez-Membrillo M, Arredondo-Zamarripa D, Ledesma-Colunga MG, Moreno-Carranza B, Martinez de la Escalera G, Colosi P, Clapp C. Díaz-Lezama N, et al. Among authors: colosi p. Lab Invest. 2016 Mar;96(3):283-95. doi: 10.1038/labinvest.2015.135. Epub 2015 Nov 16. Lab Invest. 2016. PMID: 26568297 Free article.
Soluble FLT1 Gene Therapy Alleviates Brain Arteriovenous Malformation Severity.
Zhu W, Shen F, Mao L, Zhan L, Kang S, Sun Z, Nelson J, Zhang R, Zou D, McDougall CM, Lawton MT, Vu TH, Wu Z, Scaria A, Colosi P, Forsayeth J, Su H. Zhu W, et al. Among authors: colosi p. Stroke. 2017 May;48(5):1420-1423. doi: 10.1161/STROKEAHA.116.015713. Epub 2017 Mar 21. Stroke. 2017. PMID: 28325846 Free PMC article.
79 results