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Role of zinc in human islet amyloid polypeptide aggregation.
Brender JR, Hartman K, Nanga RP, Popovych N, de la Salud Bea R, Vivekanandan S, Marsh EN, Ramamoorthy A. Brender JR, et al. Among authors: vivekanandan s. J Am Chem Soc. 2010 Jul 7;132(26):8973-83. doi: 10.1021/ja1007867. J Am Chem Soc. 2010. PMID: 20536124 Free PMC article.
A two-site mechanism for the inhibition of IAPP amyloidogenesis by zinc.
Salamekh S, Brender JR, Hyung SJ, Nanga RP, Vivekanandan S, Ruotolo BT, Ramamoorthy A. Salamekh S, et al. Among authors: vivekanandan s. J Mol Biol. 2011 Jul 8;410(2):294-306. doi: 10.1016/j.jmb.2011.05.015. Epub 2011 May 17. J Mol Biol. 2011. PMID: 21616080 Free PMC article.
Probing the sources of the apparent irreproducibility of amyloid formation: drastic changes in kinetics and a switch in mechanism due to micellelike oligomer formation at critical concentrations of IAPP.
Brender JR, Krishnamoorthy J, Sciacca MF, Vivekanandan S, D'Urso L, Chen J, La Rosa C, Ramamoorthy A. Brender JR, et al. Among authors: vivekanandan s. J Phys Chem B. 2015 Feb 19;119(7):2886-96. doi: 10.1021/jp511758w. Epub 2015 Feb 3. J Phys Chem B. 2015. PMID: 25645610
Small molecule modulators of copper-induced Abeta aggregation.
Hindo SS, Mancino AM, Braymer JJ, Liu Y, Vivekanandan S, Ramamoorthy A, Lim MH. Hindo SS, et al. Among authors: vivekanandan s. J Am Chem Soc. 2009 Nov 25;131(46):16663-5. doi: 10.1021/ja907045h. J Am Chem Soc. 2009. PMID: 19877631 Free PMC article.
104 results