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Characterization of golimumab, a human monoclonal antibody specific for human tumor necrosis factor α.
Shealy DJ, Cai A, Staquet K, Baker A, Lacy ER, Johns L, Vafa O, Gunn G 3rd, Tam S, Sague S, Wang D, Brigham-Burke M, Dalmonte P, Emmell E, Pikounis B, Bugelski PJ, Zhou H, Scallon BJ, Giles-Komar J. Shealy DJ, et al. Among authors: bugelski pj. MAbs. 2010 Jul-Aug;2(4):428-39. doi: 10.4161/mabs.12304. Epub 2010 Jul 1. MAbs. 2010. PMID: 20519961 Free PMC article.
Development of a murine model of lymph node metastases suitable for immunotoxicity studies.
Egenolf DD, Rafferty P, Brosnan K, Walker M, Jordan J, Makropoulos D, Kavalkovich K, Watson S, Johns L, Volk A, Bugelski PJ. Egenolf DD, et al. Among authors: bugelski pj. J Pharmacol Toxicol Methods. 2011 May-Jun;63(3):236-49. doi: 10.1016/j.vascn.2010.12.001. Epub 2010 Dec 13. J Pharmacol Toxicol Methods. 2011. PMID: 21156211
Modification of the Fc region of a primatized IgG antibody to human CD4 retains its ability to modulate CD4 receptors but does not deplete CD4(+) T cells in chimpanzees.
Newman R, Hariharan K, Reff M, Anderson DR, Braslawsky G, Santoro D, Hanna N, Bugelski PJ, Brigham-Burke M, Crysler C, Gagnon RC, Dal Monte P, Doyle ML, Hensley PC, Reddy MP, Sweet RW, Truneh A. Newman R, et al. Among authors: bugelski pj. Clin Immunol. 2001 Feb;98(2):164-74. doi: 10.1006/clim.2000.4975. Clin Immunol. 2001. PMID: 11161972
Monoclonal antibody-induced cytokine-release syndrome.
Bugelski PJ, Achuthanandam R, Capocasale RJ, Treacy G, Bouman-Thio E. Bugelski PJ, et al. Expert Rev Clin Immunol. 2009 Sep;5(5):499-521. doi: 10.1586/eci.09.31. Expert Rev Clin Immunol. 2009. PMID: 20477639
119 results