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Sequential activation of NFAT and c-Myc transcription factors mediates the TGF-beta switch from a suppressor to a promoter of cancer cell proliferation.
Singh G, Singh SK, König A, Reutlinger K, Nye MD, Adhikary T, Eilers M, Gress TM, Fernandez-Zapico ME, Ellenrieder V. Singh G, et al. Among authors: singh sk. J Biol Chem. 2010 Aug 27;285(35):27241-27250. doi: 10.1074/jbc.M110.100438. Epub 2010 Jun 1. J Biol Chem. 2010. PMID: 20516082 Free PMC article.
NFAT-induced histone acetylation relay switch promotes c-Myc-dependent growth in pancreatic cancer cells.
Köenig A, Linhart T, Schlengemann K, Reutlinger K, Wegele J, Adler G, Singh G, Hofmann L, Kunsch S, Büch T, Schäfer E, Gress TM, Fernandez-Zapico ME, Ellenrieder V. Köenig A, et al. Among authors: singh g. Gastroenterology. 2010 Mar;138(3):1189-99.e1-2. doi: 10.1053/j.gastro.2009.10.045. Epub 2009 Nov 6. Gastroenterology. 2010. PMID: 19900447 Free PMC article.
Disruption of a nuclear NFATc2 protein stabilization loop confers breast and pancreatic cancer growth suppression by zoledronic acid.
Singh SK, Baumgart S, Singh G, König AO, Reutlinger K, Hofbauer LC, Barth P, Gress TM, Lomberk G, Urrutia R, Fernandez-Zapico ME, Ellenrieder V. Singh SK, et al. Among authors: singh g. J Biol Chem. 2011 Aug 19;286(33):28761-28771. doi: 10.1074/jbc.M110.197533. Epub 2011 May 31. J Biol Chem. 2011. PMID: 21628454 Free PMC article.
Inflammation-induced NFATc1-STAT3 transcription complex promotes pancreatic cancer initiation by KrasG12D.
Baumgart S, Chen NM, Siveke JT, König A, Zhang JS, Singh SK, Wolf E, Bartkuhn M, Esposito I, Heßmann E, Reinecke J, Nikorowitsch J, Brunner M, Singh G, Fernandez-Zapico ME, Smyrk T, Bamlet WR, Eilers M, Neesse A, Gress TM, Billadeau DD, Tuveson D, Urrutia R, Ellenrieder V. Baumgart S, et al. Among authors: singh g, singh sk. Cancer Discov. 2014 Jun;4(6):688-701. doi: 10.1158/2159-8290.CD-13-0593. Epub 2014 Apr 2. Cancer Discov. 2014. PMID: 24694735 Free PMC article.
Antithetical NFATc1-Sox2 and p53-miR200 signaling networks govern pancreatic cancer cell plasticity.
Singh SK, Chen NM, Hessmann E, Siveke J, Lahmann M, Singh G, Voelker N, Vogt S, Esposito I, Schmidt A, Brendel C, Stiewe T, Gaedcke J, Mernberger M, Crawford HC, Bamlet WR, Zhang JS, Li XK, Smyrk TC, Billadeau DD, Hebrok M, Neesse A, Koenig A, Ellenrieder V. Singh SK, et al. Among authors: singh g. EMBO J. 2015 Feb 12;34(4):517-30. doi: 10.15252/embj.201489574. Epub 2015 Jan 13. EMBO J. 2015. PMID: 25586376 Free PMC article.
NFATc1 Links EGFR Signaling to Induction of Sox9 Transcription and Acinar-Ductal Transdifferentiation in the Pancreas.
Chen NM, Singh G, Koenig A, Liou GY, Storz P, Zhang JS, Regul L, Nagarajan S, Kühnemuth B, Johnsen SA, Hebrok M, Siveke J, Billadeau DD, Ellenrieder V, Hessmann E. Chen NM, et al. Among authors: singh g. Gastroenterology. 2015 May;148(5):1024-1034.e9. doi: 10.1053/j.gastro.2015.01.033. Epub 2015 Jan 23. Gastroenterology. 2015. PMID: 25623042 Free PMC article.
8,033 results