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Molecular pathogenesis of malignant mesothelioma.
Rascoe PA, Jupiter D, Cao X, Littlejohn JE, Smythe WR. Rascoe PA, et al. Among authors: cao x. Expert Rev Mol Med. 2012 May 24;14:e12. doi: 10.1017/erm.2012.6. Expert Rev Mol Med. 2012. PMID: 22622048 Review.
The novel BH3 α-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein-protein interactions with Bak.
Cao X, Yap JL, Newell-Rogers MK, Peddaboina C, Jiang W, Papaconstantinou HT, Jupitor D, Rai A, Jung KY, Tubin RP, Yu W, Vanommeslaeghe K, Wilder PT, MacKerell AD Jr, Fletcher S, Smythe RW. Cao X, et al. Mol Cancer. 2013 May 16;12(1):42. doi: 10.1186/1476-4598-12-42. Mol Cancer. 2013. PMID: 23680104 Free PMC article.
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