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Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes.
Zhong H, Beaulaurier J, Lum PY, Molony C, Yang X, Macneil DJ, Weingarth DT, Zhang B, Greenawalt D, Dobrin R, Hao K, Woo S, Fabre-Suver C, Qian S, Tota MR, Keller MP, Kendziorski CM, Yandell BS, Castro V, Attie AD, Kaplan LM, Schadt EE. Zhong H, et al. Among authors: molony c. PLoS Genet. 2010 May 6;6(5):e1000932. doi: 10.1371/journal.pgen.1000932. PLoS Genet. 2010. PMID: 20463879 Free PMC article.
Mapping the genetic architecture of gene expression in human liver.
Schadt EE, Molony C, Chudin E, Hao K, Yang X, Lum PY, Kasarskis A, Zhang B, Wang S, Suver C, Zhu J, Millstein J, Sieberts S, Lamb J, GuhaThakurta D, Derry J, Storey JD, Avila-Campillo I, Kruger MJ, Johnson JM, Rohl CA, van Nas A, Mehrabian M, Drake TA, Lusis AJ, Smith RC, Guengerich FP, Strom SC, Schuetz E, Rushmore TH, Ulrich R. Schadt EE, et al. Among authors: molony c. PLoS Biol. 2008 May 6;6(5):e107. doi: 10.1371/journal.pbio.0060107. PLoS Biol. 2008. PMID: 18462017 Free PMC article.
Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver.
Yang X, Zhang B, Molony C, Chudin E, Hao K, Zhu J, Gaedigk A, Suver C, Zhong H, Leeder JS, Guengerich FP, Strom SC, Schuetz E, Rushmore TH, Ulrich RG, Slatter JG, Schadt EE, Kasarskis A, Lum PY. Yang X, et al. Among authors: molony c. Genome Res. 2010 Aug;20(8):1020-36. doi: 10.1101/gr.103341.109. Epub 2010 Jun 10. Genome Res. 2010. PMID: 20538623 Free PMC article.
Identification of genes and networks driving cardiovascular and metabolic phenotypes in a mouse F2 intercross.
Derry JM, Zhong H, Molony C, MacNeil D, Guhathakurta D, Zhang B, Mudgett J, Small K, El Fertak L, Guimond A, Selloum M, Zhao W, Champy MF, Monassier L, Vogt T, Cully D, Kasarskis A, Schadt EE. Derry JM, et al. Among authors: molony c. PLoS One. 2010 Dec 14;5(12):e14319. doi: 10.1371/journal.pone.0014319. PLoS One. 2010. PMID: 21179467 Free PMC article.
A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort.
Greenawalt DM, Dobrin R, Chudin E, Hatoum IJ, Suver C, Beaulaurier J, Zhang B, Castro V, Zhu J, Sieberts SK, Wang S, Molony C, Heymsfield SB, Kemp DM, Reitman ML, Lum PY, Schadt EE, Kaplan LM. Greenawalt DM, et al. Among authors: molony c. Genome Res. 2011 Jul;21(7):1008-16. doi: 10.1101/gr.112821.110. Epub 2011 May 20. Genome Res. 2011. PMID: 21602305 Free PMC article.
Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting.
Lamb JR, Zhang C, Xie T, Wang K, Zhang B, Hao K, Chudin E, Fraser HB, Millstein J, Ferguson M, Suver C, Ivanovska I, Scott M, Philippar U, Bansal D, Zhang Z, Burchard J, Smith R, Greenawalt D, Cleary M, Derry J, Loboda A, Watters J, Poon RT, Fan ST, Yeung C, Lee NP, Guinney J, Molony C, Emilsson V, Buser-Doepner C, Zhu J, Friend S, Mao M, Shaw PM, Dai H, Luk JM, Schadt EE. Lamb JR, et al. Among authors: molony c. PLoS One. 2011;6(7):e20090. doi: 10.1371/journal.pone.0020090. Epub 2011 Jul 5. PLoS One. 2011. PMID: 21750698 Free PMC article.
56 results