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Pyruvate:ferredoxin oxidoreductase and thioredoxin reductase are involved in 5-nitroimidazole activation while flavin metabolism is linked to 5-nitroimidazole resistance in Giardia lamblia.
Leitsch D, Burgess AG, Dunn LA, Krauer KG, Tan K, Duchêne M, Upcroft P, Eckmann L, Upcroft JA. Leitsch D, et al. Among authors: upcroft p. J Antimicrob Chemother. 2011 Aug;66(8):1756-65. doi: 10.1093/jac/dkr192. Epub 2011 May 22. J Antimicrob Chemother. 2011. PMID: 21602576 Free PMC article.
Drug resistance in Giardia intestinalis.
Upcroft JA, Upcroft P, Boreham PF. Upcroft JA, et al. Among authors: upcroft p. Int J Parasitol. 1990 Jul;20(4):489-96. doi: 10.1016/0020-7519(90)90196-t. Int J Parasitol. 1990. PMID: 2210942 Review.
Quinacrine-resistant Giardia duodenalis.
Upcroft JA, Campbell RW, Upcroft P. Upcroft JA, et al. Among authors: upcroft p. Parasitology. 1996 Mar;112 ( Pt 3):309-13. doi: 10.1017/s0031182000065823. Parasitology. 1996. PMID: 8728994
97 results