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Migration of bone marrow and cord blood mesenchymal stem cells in vitro is regulated by stromal-derived factor-1-CXCR4 and hepatocyte growth factor-c-met axes and involves matrix metalloproteinases.
Son BR, Marquez-Curtis LA, Kucia M, Wysoczynski M, Turner AR, Ratajczak J, Ratajczak MZ, Janowska-Wieczorek A. Son BR, et al. Among authors: wysoczynski m. Stem Cells. 2006 May;24(5):1254-64. doi: 10.1634/stemcells.2005-0271. Epub 2006 Jan 12. Stem Cells. 2006. PMID: 16410389
Novel insight into stem cell mobilization-plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex.
Ratajczak MZ, Lee H, Wysoczynski M, Wan W, Marlicz W, Laughlin MJ, Kucia M, Janowska-Wieczorek A, Ratajczak J. Ratajczak MZ, et al. Among authors: wysoczynski m. Leukemia. 2010 May;24(5):976-85. doi: 10.1038/leu.2010.53. Epub 2010 Apr 1. Leukemia. 2010. PMID: 20357827 Free PMC article.
90 results