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Multivalent antibodies: when design surpasses evolution.
Cuesta AM, Sainz-Pastor N, Bonet J, Oliva B, Alvarez-Vallina L. Cuesta AM, et al. Trends Biotechnol. 2010 Jul;28(7):355-62. doi: 10.1016/j.tibtech.2010.03.007. Epub 2010 May 4. Trends Biotechnol. 2010. PMID: 20447706 Review.
Antibody engineering: facing new challenges in cancer therapy.
Sanz L, Cuesta AM, Compte M, Alvarez-Vallina L. Sanz L, et al. Among authors: cuesta am. Acta Pharmacol Sin. 2005 Jun;26(6):641-8. doi: 10.1111/j.1745-7254.2005.00135.x. Acta Pharmacol Sin. 2005. PMID: 15916728 Review.
Generation and characterization of monospecific and bispecific hexavalent trimerbodies.
Blanco-Toribio A, Sainz-Pastor N, Álvarez-Cienfuegos A, Merino N, Cuesta ÁM, Sánchez-Martín D, Bonet J, Santos-Valle P, Sanz L, Oliva B, Blanco FJ, Álvarez-Vallina L. Blanco-Toribio A, et al. Among authors: cuesta am. MAbs. 2013 Jan-Feb;5(1):70-9. doi: 10.4161/mabs.22698. Epub 2012 Dec 5. MAbs. 2013. PMID: 23221741 Free PMC article.
Proteasome activator complex PA28 identified as an accessible target in prostate cancer by in vivo selection of human antibodies.
Sánchez-Martín D, Martínez-Torrecuadrada J, Teesalu T, Sugahara KN, Alvarez-Cienfuegos A, Ximénez-Embún P, Fernández-Periáñez R, Martín MT, Molina-Privado I, Ruppen-Cañás I, Blanco-Toribio A, Cañamero M, Cuesta AM, Compte M, Kremer L, Bellas C, Alonso-Camino V, Guijarro-Muñoz I, Sanz L, Ruoslahti E, Alvarez-Vallina L. Sánchez-Martín D, et al. Among authors: cuesta am. Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13791-6. doi: 10.1073/pnas.1300013110. Epub 2013 Aug 5. Proc Natl Acad Sci U S A. 2013. PMID: 23918357 Free PMC article.
Intramolecular trimerization, a novel strategy for making multispecific antibodies with controlled orientation of the antigen binding domains.
Alvarez-Cienfuegos A, Nuñez-Prado N, Compte M, Cuesta AM, Blanco-Toribio A, Harwood SL, Villate M, Merino N, Bonet J, Navarro R, Muñoz-Briones C, Sørensen KM, Mølgaard K, Oliva B, Sanz L, Blanco FJ, Alvarez-Vallina L. Alvarez-Cienfuegos A, et al. Among authors: cuesta am. Sci Rep. 2016 Jun 27;6:28643. doi: 10.1038/srep28643. Sci Rep. 2016. PMID: 27345490 Free PMC article.
52 results