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Development of hexadecyloxypropyl tenofovir (CMX157) for treatment of infection caused by wild-type and nucleoside/nucleotide-resistant HIV.
Lanier ER, Ptak RG, Lampert BM, Keilholz L, Hartman T, Buckheit RW Jr, Mankowski MK, Osterling MC, Almond MR, Painter GR. Lanier ER, et al. Among authors: mankowski mk. Antimicrob Agents Chemother. 2010 Jul;54(7):2901-9. doi: 10.1128/AAC.00068-10. Epub 2010 May 3. Antimicrob Agents Chemother. 2010. PMID: 20439609 Free PMC article.
Development of a comprehensive human immunodeficiency virus type 1 screening algorithm for discovery and preclinical testing of topical microbicides.
Lackman-Smith C, Osterling C, Luckenbaugh K, Mankowski M, Snyder B, Lewis G, Paull J, Profy A, Ptak RG, Buckheit RW Jr, Watson KM, Cummins JE Jr, Sanders-Beer BE. Lackman-Smith C, et al. Antimicrob Agents Chemother. 2008 May;52(5):1768-81. doi: 10.1128/AAC.01328-07. Epub 2008 Mar 3. Antimicrob Agents Chemother. 2008. PMID: 18316528 Free PMC article.
Potent strategy to inhibit HIV-1 by binding both gp120 and gp41.
Kagiampakis I, Gharibi A, Mankowski MK, Snyder BA, Ptak RG, Alatas K, LiWang PJ. Kagiampakis I, et al. Among authors: mankowski mk. Antimicrob Agents Chemother. 2011 Jan;55(1):264-75. doi: 10.1128/AAC.00376-10. Epub 2010 Oct 18. Antimicrob Agents Chemother. 2011. PMID: 20956603 Free PMC article.
Evaluation of PD 404,182 as an anti-HIV and anti-herpes simplex virus microbicide.
Chamoun-Emanuelli AM, Bobardt M, Moncla B, Mankowski MK, Ptak RG, Gallay P, Chen Z. Chamoun-Emanuelli AM, et al. Among authors: mankowski mk. Antimicrob Agents Chemother. 2014;58(2):687-97. doi: 10.1128/AAC.02000-13. Epub 2013 Nov 11. Antimicrob Agents Chemother. 2014. PMID: 24217696 Free PMC article.
An analog of camptothecin inactive against Topoisomerase I is broadly neutralizing of HIV-1 through inhibition of Vif-dependent APOBEC3G degradation.
Bennett RP, Stewart RA, Hogan PA, Ptak RG, Mankowski MK, Hartman TL, Buckheit RW Jr, Snyder BA, Salter JD, Morales GA, Smith HC. Bennett RP, et al. Among authors: mankowski mk. Antiviral Res. 2016 Dec;136:51-59. doi: 10.1016/j.antiviral.2016.11.001. Epub 2016 Nov 5. Antiviral Res. 2016. PMID: 27825797 Free PMC article.
In vitro preclinical testing of nonoxynol-9 as potential anti-human immunodeficiency virus microbicide: a retrospective analysis of results from five laboratories.
Beer BE, Doncel GF, Krebs FC, Shattock RJ, Fletcher PS, Buckheit RW Jr, Watson K, Dezzutti CS, Cummins JE, Bromley E, Richardson-Harman N, Pallansch LA, Lackman-Smith C, Osterling C, Mankowski M, Miller SR, Catalone BJ, Welsh PA, Howett MK, Wigdahl B, Turpin JA, Reichelderfer P. Beer BE, et al. Among authors: mankowski m. Antimicrob Agents Chemother. 2006 Feb;50(2):713-23. doi: 10.1128/AAC.50.2.713-723.2006. Antimicrob Agents Chemother. 2006. PMID: 16436731 Free PMC article.
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