Ségalat L - Search Results

1

High-throughput screening and small animal models, where are we?

Giacomotto J, Ségalat L. Giacomotto J, et al. Among authors: segalat l. Br J Pharmacol. 2010 May;160(2):204-16. doi: 10.1111/j.1476-5381.2010.00725.x. Br J Pharmacol. 2010. PMID: 20423335 Free PMC article. Review.

2

Evaluation of the therapeutic potential of carbonic anhydrase inhibitors in two animal models of dystrophin deficient muscular dystrophy.

Giacomotto J, Pertl C, Borrel C, Walter MC, Bulst S, Johnsen B, Baillie DL, Lochmüller H, Thirion C, Ségalat L. Giacomotto J, et al. Among authors: segalat l. Hum Mol Genet. 2009 Nov 1;18(21):4089-101. doi: 10.1093/hmg/ddp358. Epub 2009 Jul 31. Hum Mol Genet. 2009. PMID: 19648295

3

Caenorhabditis elegans as a chemical screening tool for the study o f neuromuscular disorders. Manual and semi-automated methods.

Giacomotto J, Ségalat L, Carre-Pierrat M, Gieseler K. Giacomotto J, et al. Among authors: segalat l. Methods. 2012 Jan;56(1):103-13. doi: 10.1016/j.ymeth.2011.10.010. Epub 2011 Oct 21. Methods. 2012. PMID: 22041718

4

Blocking of striated muscle degeneration by serotonin in C. elegans.

Carre-Pierrat M, Mariol MC, Chambonnier L, Laugraud A, Heskia F, Giacomotto J, Ségalat L. Carre-Pierrat M, et al. Among authors: segalat l. J Muscle Res Cell Motil. 2006;27(3-4):253-8. doi: 10.1007/s10974-006-9070-9. Epub 2006 Jun 22. J Muscle Res Cell Motil. 2006. PMID: 16791712

5

Metabolic profiling strategy of Caenorhabditis elegans by whole-organism nuclear magnetic resonance.

Blaise BJ, Giacomotto J, Triba MN, Toulhoat P, Piotto M, Emsley L, Ségalat L, Dumas ME, Elena B. Blaise BJ, et al. Among authors: segalat l. J Proteome Res. 2009 May;8(5):2542-50. doi: 10.1021/pr900012d. J Proteome Res. 2009. PMID: 19267476

6

Metabotyping of Caenorhabditis elegans reveals latent phenotypes.

Blaise BJ, Giacomotto J, Elena B, Dumas ME, Toulhoat P, Ségalat L, Emsley L. Blaise BJ, et al. Among authors: segalat l. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19808-12. doi: 10.1073/pnas.0707393104. Epub 2007 Dec 5. Proc Natl Acad Sci U S A. 2007. PMID: 18077412 Free PMC article.

7

Chemical genetics unveils a key role of mitochondrial dynamics, cytochrome c release and IP3R activity in muscular dystrophy.

Giacomotto J, Brouilly N, Walter L, Mariol MC, Berger J, Ségalat L, Becker TS, Currie PD, Gieseler K. Giacomotto J, et al. Among authors: segalat l. Hum Mol Genet. 2013 Nov 15;22(22):4562-78. doi: 10.1093/hmg/ddt302. Epub 2013 Jun 25. Hum Mol Genet. 2013. PMID: 23804750

8

Invertebrate animal models of diseases as screening tools in drug discovery.

Ségalat L. Ségalat L. ACS Chem Biol. 2007 Apr 24;2(4):231-6. doi: 10.1021/cb700009m. ACS Chem Biol. 2007. PMID: 17455900 Review.

9

Dystrophin-dependent muscle degeneration requires a fully functional contractile machinery to occur in C. elegans.

Mariol MC, Martin E, Chambonnier L, Ségalat L. Mariol MC, et al. Among authors: segalat l. Neuromuscul Disord. 2007 Jan;17(1):56-60. doi: 10.1016/j.nmd.2006.09.012. Epub 2006 Nov 28. Neuromuscul Disord. 2007. PMID: 17134897

10

Pre-clinical study of 21 approved drugs in the mdx mouse.

Carre-Pierrat M, Lafoux A, Tanniou G, Chambonnier L, Divet A, Fougerousse F, Huchet-Cadiou C, Ségalat L. Carre-Pierrat M, et al. Among authors: segalat l. Neuromuscul Disord. 2011 May;21(5):313-27. doi: 10.1016/j.nmd.2011.01.005. Epub 2011 Mar 9. Neuromuscul Disord. 2011. PMID: 21392993

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