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Tumor necrosis factor receptor-associated factor 1 (TRAF1) deficiency attenuates atherosclerosis in mice by impairing monocyte recruitment to the vessel wall.
Missiou A, Köstlin N, Varo N, Rudolf P, Aichele P, Ernst S, Münkel C, Walter C, Stachon P, Sommer B, Pfeifer D, Zirlik K, MacFarlane L, Wolf D, Tsitsikov E, Bode C, Libby P, Zirlik A. Missiou A, et al. Among authors: aichele p. Circulation. 2010 May 11;121(18):2033-44. doi: 10.1161/CIRCULATIONAHA.109.895037. Epub 2010 Apr 26. Circulation. 2010. PMID: 20421522 Free PMC article.
TRAF5 deficiency accelerates atherogenesis in mice by increasing inflammatory cell recruitment and foam cell formation.
Missiou A, Rudolf P, Stachon P, Wolf D, Varo N, Aichele P, Colberg C, Hoppe N, Ernst S, Münkel C, Walter C, Sommer B, Hilgendorf I, Nakano H, Bode C, Zirlik A. Missiou A, et al. Among authors: aichele p. Circ Res. 2010 Sep 17;107(6):757-66. doi: 10.1161/CIRCRESAHA.110.219295. Epub 2010 Jul 22. Circ Res. 2010. PMID: 20651286 Clinical Trial.
Coinhibitory suppression of T cell activation by CD40 protects against obesity and adipose tissue inflammation in mice.
Wolf D, Jehle F, Michel NA, Bukosza EN, Rivera J, Chen YC, Hoppe N, Dufner B, Rodriguez AO, Colberg C, Nieto L, Rupprecht B, Wiedemann A, Schulte L, Peikert A, Bassler N, Lozhkin A, Hergeth SP, Stachon P, Hilgendorf I, Willecke F, von Zur Mühlen C, von Elverfeldt D, Binder CJ, Aichele P, Varo N, Febbraio MA, Libby P, Bode C, Peter K, Zirlik A. Wolf D, et al. Among authors: aichele p. Circulation. 2014 Jun 10;129(23):2414-25. doi: 10.1161/CIRCULATIONAHA.113.008055. Epub 2014 Mar 24. Circulation. 2014. PMID: 24664276
Activation of cellular death programs associated with immunosenescence-like phenotype in TPPII knockout mice.
Huai J, Firat E, Nil A, Million D, Gaedicke S, Kanzler B, Freudenberg M, van Endert P, Kohler G, Pahl HL, Aichele P, Eichmann K, Niedermann G. Huai J, et al. Among authors: aichele p. Proc Natl Acad Sci U S A. 2008 Apr 1;105(13):5177-82. doi: 10.1073/pnas.0801413105. Epub 2008 Mar 24. Proc Natl Acad Sci U S A. 2008. PMID: 18362329 Free PMC article.
Studying NK cell/dendritic cell interactions.
Lucas M, Vonarbourg C, Aichele P, Diefenbach A. Lucas M, et al. Among authors: aichele p. Methods Mol Biol. 2010;612:97-126. doi: 10.1007/978-1-60761-362-6_8. Methods Mol Biol. 2010. PMID: 20033637
73 results