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A novel mechanism for azoreduction.
Ryan A, Laurieri N, Westwood I, Wang CJ, Lowe E, Sim E. Ryan A, et al. Among authors: westwood i. J Mol Biol. 2010 Jul 2;400(1):24-37. doi: 10.1016/j.jmb.2010.04.023. Epub 2010 Apr 24. J Mol Biol. 2010. PMID: 20417637
Role of tyrosine 131 in the active site of paAzoR1, an azoreductase with specificity for the inflammatory bowel disease prodrug balsalazide.
Wang CJ, Laurieri N, Abuhammad A, Lowe E, Westwood I, Ryan A, Sim E. Wang CJ, et al. Among authors: westwood i. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Jan 1;66(Pt 1):2-7. doi: 10.1107/S1744309109044741. Epub 2009 Dec 25. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20057057 Free PMC article.
Arylamine N-acetyltransferases.
Sim E, Westwood I, Fullam E. Sim E, et al. Among authors: westwood i. Expert Opin Drug Metab Toxicol. 2007 Apr;3(2):169-84. doi: 10.1517/17425255.3.2.169. Expert Opin Drug Metab Toxicol. 2007. PMID: 17428149 Review.
53 results