Laurieri N - Search Results

1

Ryan A, Laurieri N, Westwood I, Wang CJ, Lowe E, Sim E. Ryan A, et al. Among authors: laurieri n. J Mol Biol. 2010 Jul 2;400(1):24-37. doi: 10.1016/j.jmb.2010.04.023. Epub 2010 Apr 24. J Mol Biol. 2010. PMID: 20417637

2

Role of tyrosine 131 in the active site of paAzoR1, an azoreductase with specificity for the inflammatory bowel disease prodrug balsalazide.

Wang CJ, Laurieri N, Abuhammad A, Lowe E, Westwood I, Ryan A, Sim E. Wang CJ, et al. Among authors: laurieri n. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Jan 1;66(Pt 1):2-7. doi: 10.1107/S1744309109044741. Epub 2009 Dec 25. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20057057 Free PMC article.

3

Reaction mechanism of azoreductases suggests convergent evolution with quinone oxidoreductases.

Ryan A, Wang CJ, Laurieri N, Westwood I, Sim E. Ryan A, et al. Among authors: laurieri n. Protein Cell. 2010 Aug;1(8):780-90. doi: 10.1007/s13238-010-0090-2. Epub 2010 Aug 28. Protein Cell. 2010. PMID: 21203919 Free PMC article.

4

Activation of nitrofurazone by azoreductases: multiple activities in one enzyme.

Ryan A, Kaplan E, Laurieri N, Lowe E, Sim E. Ryan A, et al. Among authors: laurieri n. Sci Rep. 2011;1:63. doi: 10.1038/srep00063. Epub 2011 Aug 12. Sci Rep. 2011. PMID: 22355582 Free PMC article.

5

Selective small molecule inhibitors of the potential breast cancer marker, human arylamine N-acetyltransferase 1, and its murine homologue, mouse arylamine N-acetyltransferase 2.

Russell AJ, Westwood IM, Crawford MH, Robinson J, Kawamura A, Redfield C, Laurieri N, Lowe ED, Davies SG, Sim E. Russell AJ, et al. Among authors: laurieri n. Bioorg Med Chem. 2009 Jan 15;17(2):905-18. doi: 10.1016/j.bmc.2008.11.032. Epub 2008 Nov 19. Bioorg Med Chem. 2009. PMID: 19059786

6

Prospective virtual screening with Ultrafast Shape Recognition: the identification of novel inhibitors of arylamine N-acetyltransferases.

Ballester PJ, Westwood I, Laurieri N, Sim E, Richards WG. Ballester PJ, et al. Among authors: laurieri n. J R Soc Interface. 2010 Feb 6;7(43):335-42. doi: 10.1098/rsif.2009.0170. Epub 2009 Jul 8. J R Soc Interface. 2010. PMID: 19586957 Free PMC article.

7

Temperature stability of proteins essential for the intracellular survival of Mycobacterium tuberculosis.

Lack NA, Kawamura A, Fullam E, Laurieri N, Beard S, Russell AJ, Evangelopoulos D, Westwood I, Sim E. Lack NA, et al. Among authors: laurieri n. Biochem J. 2009 Mar 1;418(2):369-78. doi: 10.1042/BJ20082011. Biochem J. 2009. PMID: 19014350

8

Small molecule colorimetric probes for specific detection of human arylamine N-acetyltransferase 1, a potential breast cancer biomarker.

Laurieri N, Crawford MH, Kawamura A, Westwood IM, Robinson J, Fletcher AM, Davies SG, Sim E, Russell AJ. Laurieri N, et al. J Am Chem Soc. 2010 Mar 17;132(10):3238-9. doi: 10.1021/ja909165u. J Am Chem Soc. 2010. PMID: 20170182

9

Differences between murine arylamine N-acetyltransferase type 1 and human arylamine N-acetyltransferase type 2 defined by substrate specificity and inhibitor binding.

Laurieri N, Kawamura A, Westwood IM, Varney A, Morris E, Russell AJ, Stanley LA, Sim E. Laurieri N, et al. BMC Pharmacol Toxicol. 2014 Nov 29;15:68. doi: 10.1186/2050-6511-15-68. BMC Pharmacol Toxicol. 2014. PMID: 25432241 Free PMC article.

10

Arylamine N-acetyltransferases--from drug metabolism and pharmacogenetics to identification of novel targets for pharmacological intervention.

Sim E, Fakis G, Laurieri N, Boukouvala S. Sim E, et al. Among authors: laurieri n. Adv Pharmacol. 2012;63:169-205. doi: 10.1016/B978-0-12-398339-8.00005-7. Adv Pharmacol. 2012. PMID: 22776642 Review.

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