Houghton JL - Search Results

1

The future of aminoglycosides: the end or renaissance?

Houghton JL, Green KD, Chen W, Garneau-Tsodikova S. Houghton JL, et al. Chembiochem. 2010 May 3;11(7):880-902. doi: 10.1002/cbic.200900779. Chembiochem. 2010. PMID: 20397253 Free article. Review.

2

Exploring the substrate promiscuity of drug-modifying enzymes for the chemoenzymatic generation of N-acylated aminoglycosides.

Green KD, Chen W, Houghton JL, Fridman M, Garneau-Tsodikova S. Green KD, et al. Among authors: houghton jl. Chembiochem. 2010 Jan 4;11(1):119-26. doi: 10.1002/cbic.200900584. Chembiochem. 2010. PMID: 19899089 Free article.

3

Chemical and structural insights into the regioversatility of the aminoglycoside acetyltransferase Eis.

Houghton JL, Biswas T, Chen W, Tsodikov OV, Garneau-Tsodikova S. Houghton JL, et al. Chembiochem. 2013 Nov 4;14(16):2127-35. doi: 10.1002/cbic.201300359. Epub 2013 Sep 17. Chembiochem. 2013. PMID: 24106131 Free PMC article.

4

Dissecting the cosubstrate structure requirements of the Staphylococcus aureus aminoglycoside resistance enzyme ANT(4').

Porter VR, Green KD, Zolova OE, Houghton JL, Garneau-Tsodikova S. Porter VR, et al. Among authors: houghton jl. Biochem Biophys Res Commun. 2010 Dec 3;403(1):85-90. doi: 10.1016/j.bbrc.2010.10.119. Epub 2010 Oct 30. Biochem Biophys Res Commun. 2010. PMID: 21040710

5

Biochemical and structural analysis of aminoglycoside acetyltransferase Eis from Anabaena variabilis.

Pricer RE, Houghton JL, Green KD, Mayhoub AS, Garneau-Tsodikova S. Pricer RE, et al. Among authors: houghton jl. Mol Biosyst. 2012 Oct 30;8(12):3305-13. doi: 10.1039/c2mb25341k. Mol Biosyst. 2012. PMID: 23090428 Free PMC article.

6

Unexpected N-acetylation of capreomycin by mycobacterial Eis enzymes.

Houghton JL, Green KD, Pricer RE, Mayhoub AS, Garneau-Tsodikova S. Houghton JL, et al. J Antimicrob Chemother. 2013 Apr;68(4):800-5. doi: 10.1093/jac/dks497. Epub 2012 Dec 11. J Antimicrob Chemother. 2013. PMID: 23233486 Free PMC article.

7

Synthesis and Biological Activity of Mono- and Di-N-acylated Aminoglycosides.

Thamban Chandrika N, Green KD, Houghton JL, Garneau-Tsodikova S. Thamban Chandrika N, et al. Among authors: houghton jl. ACS Med Chem Lett. 2015 Sep 30;6(11):1134-9. doi: 10.1021/acsmedchemlett.5b00255. eCollection 2015 Nov 12. ACS Med Chem Lett. 2015. PMID: 26617967 Free PMC article.

8

The structural basis for substrate versatility of chloramphenicol acetyltransferase CATI.

Biswas T, Houghton JL, Garneau-Tsodikova S, Tsodikov OV. Biswas T, et al. Among authors: houghton jl. Protein Sci. 2012 Apr;21(4):520-30. doi: 10.1002/pro.2036. Epub 2012 Mar 6. Protein Sci. 2012. PMID: 22294317 Free PMC article.

9

Underscoring the influence of inorganic chemistry on nuclear imaging with radiometals.

Zeglis BM, Houghton JL, Evans MJ, Viola-Villegas N, Lewis JS. Zeglis BM, et al. Among authors: houghton jl. Inorg Chem. 2014 Feb 17;53(4):1880-99. doi: 10.1021/ic401607z. Epub 2013 Dec 6. Inorg Chem. 2014. PMID: 24313747 Free PMC article.

10

Dual-Modality Imaging of Prostate Cancer with a Fluorescent and Radiogallium-Labeled Gastrin-Releasing Peptide Receptor Antagonist.

Zhang H, Desai P, Koike Y, Houghton J, Carlin S, Tandon N, Touijer K, Weber WA. Zhang H, et al. J Nucl Med. 2017 Jan;58(1):29-35. doi: 10.2967/jnumed.116.176099. Epub 2016 Aug 11. J Nucl Med. 2017. PMID: 27516447 Free PMC article.

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