Kempf DJ - Search Results

1

Identification of proteasome gene regulation in a rat model for HIV protease inhibitor-induced hyperlipidemia.

Waring JF, Ciurlionis R, Marsh K, Klein LL, Degoey DA, Randolph JT, Spear B, Kempf DJ. Waring JF, et al. Among authors: kempf dj. Arch Toxicol. 2010 Apr;84(4):263-70. doi: 10.1007/s00204-010-0527-7. Epub 2010 Mar 6. Arch Toxicol. 2010. PMID: 20213465

2

Oximinoarylsulfonamides as potent HIV protease inhibitors.

Yeung CM, Klein LL, Flentge CA, Randolph JT, Zhao C, Sun M, Dekhtyar T, Stoll VS, Kempf DJ. Yeung CM, et al. Among authors: kempf dj. Bioorg Med Chem Lett. 2005 May 2;15(9):2275-8. doi: 10.1016/j.bmcl.2005.03.008. Bioorg Med Chem Lett. 2005. PMID: 15837308

3

Practical preclinical model for assessing the potential for unconjugated hyperbilirubinemia produced by human immunodeficiency virus protease inhibitors.

Kempf DJ, Waring JF, Morfitt DC, Werner P, Ebert B, Mitten M, Nguyen B, Randolph JT, DeGoey DA, Klein LL, Marsh K. Kempf DJ, et al. Antimicrob Agents Chemother. 2006 Feb;50(2):762-4. doi: 10.1128/AAC.50.2.762-764.2006. Antimicrob Agents Chemother. 2006. PMID: 16436740 Free PMC article.

4

Liver transcriptomic changes associated with ritonavir-induced hyperlipidemia in sensitive and resistant strains of rats.

Yang Y, Dahly-Vernon AJ, Blomme EA, Lai-Zhang J, Kempf DJ, Marsh KC, Harrington YA, Nye SH, Evans DL, Roman RJ, Jacob HJ, Waring JF. Yang Y, et al. Among authors: kempf dj. Vet J. 2010 Jul;185(1):75-82. doi: 10.1016/j.tvjl.2010.04.017. Epub 2010 May 23. Vet J. 2010. PMID: 20547082

5

Synthesis and antiviral activity of P1' arylsulfonamide azacyclic urea HIV protease inhibitors.

Huang PP, Randolph JT, Klein LL, Vasavanonda S, Dekhtyar T, Stoll VS, Kempf DJ. Huang PP, et al. Among authors: kempf dj. Bioorg Med Chem Lett. 2004 Aug 2;14(15):4075-8. doi: 10.1016/j.bmcl.2004.05.036. Bioorg Med Chem Lett. 2004. PMID: 15225729

6

Synthesis and activity of N-acyl azacyclic urea HIV-1 protease inhibitors with high potency against multiple drug resistant viral strains.

Zhao C, Sham HL, Sun M, Stoll VS, Stewart KD, Lin S, Mo H, Vasavanonda S, Saldivar A, Park C, McDonald EJ, Marsh KC, Klein LL, Kempf DJ, Norbeck DW. Zhao C, et al. Among authors: kempf dj. Bioorg Med Chem Lett. 2005 Dec 15;15(24):5499-503. doi: 10.1016/j.bmcl.2005.08.093. Epub 2005 Oct 3. Bioorg Med Chem Lett. 2005. PMID: 16203141

7

Synthesis, antiviral activity, and pharmacokinetic evaluation of P3 pyridylmethyl analogs of oximinoarylsulfonyl HIV-1 protease inhibitors.

Randolph JT, Huang PP, Flosi WJ, DeGoey D, Klein LL, Yeung CM, Flentge C, Sun M, Zhao C, Dekhtyar T, Mo H, Colletti L, Kati W, Marsh KC, Molla A, Kempf DJ. Randolph JT, et al. Among authors: kempf dj. Bioorg Med Chem. 2006 Jun 15;14(12):4035-46. doi: 10.1016/j.bmc.2006.02.013. Epub 2006 Feb 28. Bioorg Med Chem. 2006. PMID: 16504523

8

Pharmacokinetic enhancement of the hepatitis C virus protease inhibitors VX-950 and SCH 503034 by co-dosing with ritonavir.

Kempf DJ, Klein C, Chen HJ, Klein LL, Yeung C, Randolph JT, Lau YY, Chovan LE, Guan Z, Hernandez L, Turner TM, Dandliker PJ, Marsh KC. Kempf DJ, et al. Antivir Chem Chemother. 2007;18(3):163-7. doi: 10.1177/095632020701800306. Antivir Chem Chemother. 2007. PMID: 17626600 Free article.

9

A human immunodeficiency virus protease inhibitor is a novel functional inhibitor of human pregnane X receptor.

Healan-Greenberg C, Waring JF, Kempf DJ, Blomme EA, Tirona RG, Kim RB. Healan-Greenberg C, et al. Among authors: kempf dj. Drug Metab Dispos. 2008 Mar;36(3):500-7. doi: 10.1124/dmd.107.019547. Epub 2007 Dec 20. Drug Metab Dispos. 2008. PMID: 18096673

10

Characterization of a novel human immunodeficiency virus type 1 protease inhibitor, A-790742.

Dekhtyar T, Ng TI, Lu L, Masse S, DeGoey DA, Flosi WJ, Grampovnik DJ, Klein LL, Kempf DJ, Molla A. Dekhtyar T, et al. Among authors: kempf dj. Antimicrob Agents Chemother. 2008 Apr;52(4):1337-44. doi: 10.1128/AAC.01132-07. Epub 2008 Jan 22. Antimicrob Agents Chemother. 2008. PMID: 18212102 Free PMC article.

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