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Molecular pharmacology and antitumor activity of PHT-427, a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor.
Meuillet EJ, Zuohe S, Lemos R, Ihle N, Kingston J, Watkins R, Moses SA, Zhang S, Du-Cuny L, Herbst R, Jacoby JJ, Zhou LL, Ahad AM, Mash EA, Kirkpatrick DL, Powis G. Meuillet EJ, et al. Among authors: watkins r. Mol Cancer Ther. 2010 Mar;9(3):706-17. doi: 10.1158/1535-7163.MCT-09-0985. Epub 2010 Mar 2. Mol Cancer Ther. 2010. PMID: 20197390 Free PMC article.
Human PXR forms a tryptophan zipper-mediated homodimer.
Noble SM, Carnahan VE, Moore LB, Luntz T, Wang H, Ittoop OR, Stimmel JB, Davis-Searles PR, Watkins RE, Wisely GB, LeCluyse E, Tripathy A, McDonnell DP, Redinbo MR. Noble SM, et al. Among authors: watkins re. Biochemistry. 2006 Jul 18;45(28):8579-89. doi: 10.1021/bi0602821. Biochemistry. 2006. PMID: 16834332 Free PMC article.
WITHDRAWN: Neoadjuvant therapy leads to objective response in intrahepatic cholangiocarcinoma.
Van Treeck BJ, Olave MC, Watkins RD, Lu H, Moreira RK, Mounajjed T, Johnson MJ, Smith CY, Ilyas SI, Tran NH, Jenkins SM, Reed KA, Smoot R, Mahipal A, Allende D, Graham RP. Van Treeck BJ, et al. Among authors: watkins rd. HPB (Oxford). 2024 Apr 24:S1365-182X(24)01277-2. doi: 10.1016/j.hpb.2024.04.011. Online ahead of print. HPB (Oxford). 2024. PMID: 38789383
Neoadjuvant therapy leads to objective response in intrahepatic cholangiocarcinoma.
Van Treeck BJ, Olave MC, Watkins RD, Lu H, Moreira RK, Mounajjed T, Johnson MJ, Smith CY, Ilyas SI, Tran NH, Jenkins SM, Reed KA, Smoot R, Mahipal A, Allende D, Graham RP. Van Treeck BJ, et al. Among authors: watkins rd. HPB (Oxford). 2024 Apr 23:S1365-182X(24)01259-0. doi: 10.1016/j.hpb.2024.04.003. Online ahead of print. HPB (Oxford). 2024. PMID: 38705793
804 results