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Beta-catenin/Tcf-4 inhibition after progastrin targeting reduces growth and drives differentiation of intestinal tumors.
Pannequin J, Delaunay N, Buchert M, Surrel F, Bourgaux JF, Ryan J, Boireau S, Coelho J, Pélegrin A, Singh P, Shulkes A, Yim M, Baldwin GS, Pignodel C, Lambeau G, Jay P, Joubert D, Hollande F. Pannequin J, et al. Among authors: joubert d. Gastroenterology. 2007 Nov;133(5):1554-68. doi: 10.1053/j.gastro.2007.08.023. Epub 2007 Oct 24. Gastroenterology. 2007. PMID: 17920061
Symplekin promotes tumorigenicity by up-regulating claudin-2 expression.
Buchert M, Papin M, Bonnans C, Darido C, Raye WS, Garambois V, Pélegrin A, Bourgaux JF, Pannequin J, Joubert D, Hollande F. Buchert M, et al. Among authors: joubert d. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2628-33. doi: 10.1073/pnas.0903747107. Epub 2010 Jan 25. Proc Natl Acad Sci U S A. 2010. PMID: 20133805 Free PMC article.
Essential requirement for β-arrestin2 in mouse intestinal tumors with elevated Wnt signaling.
Bonnans C, Flacelière M, Grillet F, Dantec C, Desvignes JP, Pannequin J, Severac D, Dubois E, Bibeau F, Escriou V, Crespy P, Journot L, Hollande F, Joubert D. Bonnans C, et al. Among authors: joubert d. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):3047-52. doi: 10.1073/pnas.1109457109. Epub 2012 Feb 6. Proc Natl Acad Sci U S A. 2012. PMID: 22315403 Free PMC article.
Autocrine Secretion of Progastrin Promotes the Survival and Self-Renewal of Colon Cancer Stem-like Cells.
Giraud J, Failla LM, Pascussi JM, Lagerqvist EL, Ollier J, Finetti P, Bertucci F, Ya C, Gasmi I, Bourgaux JF, Prudhomme M, Mazard T, Ait-Arsa I, Houhou L, Birnbaum D, Pélegrin A, Vincent C, Ryall JG, Joubert D, Pannequin J, Hollande F. Giraud J, et al. Among authors: joubert d. Cancer Res. 2016 Jun 15;76(12):3618-28. doi: 10.1158/0008-5472.CAN-15-1497. Epub 2016 May 4. Cancer Res. 2016. PMID: 27197176
178 results