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Identification of 2-anilino-9-methoxy-5,7-dihydro-6H-pyrimido[5,4-d][1]benzazepin-6-ones as dual PLK1/VEGF-R2 kinase inhibitor chemotypes by structure-based lead generation.
J Med Chem. 2010 Mar 25;53(6):2433-42. doi: 10.1021/jm901388c.
J Med Chem. 2010.
PMID: 20170163
1-Aryl-4,6-dihydropyrazolo[4,3-d][1]benzazepin-5(1H)-ones: a new class of antiproliferative agents with selectivity for human leukemia and breast cancer cell lines.
Kohfeld S, Jones PG, Totzke F, Schächtele C, Kubbutat MH, Kunick C.
Kohfeld S, et al.
Eur J Med Chem. 2007 Nov-Dec;42(11-12):1317-24. doi: 10.1016/j.ejmech.2007.02.007. Epub 2007 Mar 1.
Eur J Med Chem. 2007.
PMID: 17448574
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Development of 5-benzylpaullones and paullone-9-carboxylic acid alkyl esters as selective inhibitors of mitochondrial malate dehydrogenase (mMDH).
Becker A, Kohfeld S, Lader A, Preu L, Pies T, Wieking K, Ferandin Y, Knockaert M, Meijer L, Kunick C.
Becker A, et al. Among authors: kohfeld s.
Eur J Med Chem. 2010 Jan;45(1):335-42. doi: 10.1016/j.ejmech.2009.10.018. Epub 2009 Oct 14.
Eur J Med Chem. 2010.
PMID: 19906467
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