Gardner KH - Search Results

1

Coactivator recruitment: a new role for PAS domains in transcriptional regulation by the bHLH-PAS family.

Partch CL, Gardner KH. Partch CL, et al. Among authors: gardner kh. J Cell Physiol. 2010 Jun;223(3):553-7. doi: 10.1002/jcp.22067. J Cell Physiol. 2010. PMID: 20112293 Free PMC article. Review.

2

Molecular basis of coiled coil coactivator recruitment by the aryl hydrocarbon receptor nuclear translocator (ARNT).

Partch CL, Card PB, Amezcua CA, Gardner KH. Partch CL, et al. Among authors: gardner kh. J Biol Chem. 2009 May 29;284(22):15184-92. doi: 10.1074/jbc.M808479200. Epub 2009 Mar 26. J Biol Chem. 2009. PMID: 19324882 Free PMC article.

3

Coactivators necessary for transcriptional output of the hypoxia inducible factor, HIF, are directly recruited by ARNT PAS-B.

Partch CL, Gardner KH. Partch CL, et al. Among authors: gardner kh. Proc Natl Acad Sci U S A. 2011 May 10;108(19):7739-44. doi: 10.1073/pnas.1101357108. Epub 2011 Apr 21. Proc Natl Acad Sci U S A. 2011. PMID: 21512126 Free PMC article.

4

Coiled-coil coactivators play a structural role mediating interactions in hypoxia-inducible factor heterodimerization.

Guo Y, Scheuermann TH, Partch CL, Tomchick DR, Gardner KH. Guo Y, et al. Among authors: gardner kh. J Biol Chem. 2015 Mar 20;290(12):7707-21. doi: 10.1074/jbc.M114.632786. Epub 2015 Jan 27. J Biol Chem. 2015. PMID: 25627682 Free PMC article.

5

Regulation of C-type lectin antimicrobial activity by a flexible N-terminal prosegment.

Mukherjee S, Partch CL, Lehotzky RE, Whitham CV, Chu H, Bevins CL, Gardner KH, Hooper LV. Mukherjee S, et al. Among authors: gardner kh. J Biol Chem. 2009 Feb 20;284(8):4881-8. doi: 10.1074/jbc.M808077200. Epub 2008 Dec 18. J Biol Chem. 2009. PMID: 19095652 Free PMC article.

6

Molecular basis for peptidoglycan recognition by a bactericidal lectin.

Lehotzky RE, Partch CL, Mukherjee S, Cash HL, Goldman WE, Gardner KH, Hooper LV. Lehotzky RE, et al. Among authors: gardner kh. Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7722-7. doi: 10.1073/pnas.0909449107. Epub 2010 Apr 9. Proc Natl Acad Sci U S A. 2010. PMID: 20382864 Free PMC article.

7

The three Rs of transcription: recruit, retain, and recycle.

Motta-Mena LB, Partch CL, Gardner KH. Motta-Mena LB, et al. Among authors: gardner kh. Mol Cell. 2010 Dec 22;40(6):855-8. doi: 10.1016/j.molcel.2010.12.010. Mol Cell. 2010. PMID: 21172650 Free PMC article.

8

Regulating the ARNT/TACC3 axis: multiple approaches to manipulating protein/protein interactions with small molecules.

Guo Y, Partch CL, Key J, Card PB, Pashkov V, Patel A, Bruick RK, Wurdak H, Gardner KH. Guo Y, et al. Among authors: gardner kh. ACS Chem Biol. 2013 Mar 15;8(3):626-35. doi: 10.1021/cb300604u. Epub 2012 Dec 26. ACS Chem Biol. 2013. PMID: 23240775 Free PMC article.

9

Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.

Scheuermann TH, Tomchick DR, Machius M, Guo Y, Bruick RK, Gardner KH. Scheuermann TH, et al. Among authors: gardner kh. Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):450-5. doi: 10.1073/pnas.0808092106. Epub 2009 Jan 7. Proc Natl Acad Sci U S A. 2009. PMID: 19129502 Free PMC article.

10

Principles of ligand binding within a completely buried cavity in HIF2alpha PAS-B.

Key J, Scheuermann TH, Anderson PC, Daggett V, Gardner KH. Key J, et al. Among authors: gardner kh. J Am Chem Soc. 2009 Dec 9;131(48):17647-54. doi: 10.1021/ja9073062. J Am Chem Soc. 2009. PMID: 19950993 Free PMC article.

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