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IKK connects autophagy to major stress pathways.
Criollo A, Senovilla L, Authier H, Maiuri MC, Morselli E, Vitale I, Kepp O, Tasdemir E, Galluzzi L, Shen S, Tailler M, Delahaye N, Tesniere A, De Stefano D, Younes AB, Harper F, Pierron G, Lavandero S, Zitvogel L, Israel A, Baud V, Kroemer G. Criollo A, et al. Among authors: de stefano d. Autophagy. 2010 Jan;6(1):189-91. doi: 10.4161/auto.6.1.10818. Autophagy. 2010. PMID: 20110771 Review.
The IKK complex contributes to the induction of autophagy.
Criollo A, Senovilla L, Authier H, Maiuri MC, Morselli E, Vitale I, Kepp O, Tasdemir E, Galluzzi L, Shen S, Tailler M, Delahaye N, Tesniere A, De Stefano D, Younes AB, Harper F, Pierron G, Lavandero S, Zitvogel L, Israel A, Baud V, Kroemer G. Criollo A, et al. Among authors: de stefano d. EMBO J. 2010 Feb 3;29(3):619-31. doi: 10.1038/emboj.2009.364. Epub 2009 Dec 3. EMBO J. 2010. PMID: 19959994 Free PMC article.
A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR.
Tosco A, De Gregorio F, Esposito S, De Stefano D, Sana I, Ferrari E, Sepe A, Salvadori L, Buonpensiero P, Di Pasqua A, Grassia R, Leone CA, Guido S, De Rosa G, Lusa S, Bona G, Stoll G, Maiuri MC, Mehta A, Kroemer G, Maiuri L, Raia V. Tosco A, et al. Among authors: de gregorio f, de rosa g, de stefano d. Cell Death Differ. 2016 Aug;23(8):1380-93. doi: 10.1038/cdd.2016.22. Epub 2016 Apr 1. Cell Death Differ. 2016. PMID: 27035618 Free PMC article. Clinical Trial.
Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation.
De Stefano D, Villella VR, Esposito S, Tosco A, Sepe A, De Gregorio F, Salvadori L, Grassia R, Leone CA, De Rosa G, Maiuri MC, Pettoello-Mantovani M, Guido S, Bossi A, Zolin A, Venerando A, Pinna LA, Mehta A, Bona G, Kroemer G, Maiuri L, Raia V. De Stefano D, et al. Among authors: de gregorio f, de rosa g. Autophagy. 2014;10(11):2053-74. doi: 10.4161/15548627.2014.973737. Autophagy. 2014. PMID: 25350163 Free PMC article. Clinical Trial.
Cannabidiol inhibits inducible nitric oxide synthase protein expression and nitric oxide production in beta-amyloid stimulated PC12 neurons through p38 MAP kinase and NF-kappaB involvement.
Esposito G, De Filippis D, Maiuri MC, De Stefano D, Carnuccio R, Iuvone T. Esposito G, et al. Among authors: de stefano d, de filippis d. Neurosci Lett. 2006 May 15;399(1-2):91-5. doi: 10.1016/j.neulet.2006.01.047. Epub 2006 Feb 21. Neurosci Lett. 2006. PMID: 16490313
73 results