Savino M - Search Results

1

Water soluble cationic perylene derivatives as possible telomerase inhibitors: the search for selective G-quadruplex targeting.

Micheli E, D'Ambrosio D, Franceschin M, Savino M. Micheli E, et al. Among authors: savino m. Mini Rev Med Chem. 2009 Dec;9(14):1622-32. doi: 10.2174/138955709791012274. Mini Rev Med Chem. 2009. PMID: 20088777 Review.

2

Specific interactions with intra- and intermolecular G-quadruplex DNA structures by hydrosoluble coronene derivatives: a new class of telomerase inhibitors.

Franceschin M, Alvino A, Casagrande V, Mauriello C, Pascucci E, Savino M, Ortaggi G, Bianco A. Franceschin M, et al. Among authors: savino m. Bioorg Med Chem. 2007 Feb 15;15(4):1848-58. doi: 10.1016/j.bmc.2006.11.032. Epub 2006 Nov 19. Bioorg Med Chem. 2007. PMID: 17150364

3

New highly hydrosoluble and not self-aggregated perylene derivatives with three and four polar side-chains as G-quadruplex telomere targeting agents and telomerase inhibitors.

Franceschin M, Pascucci E, Alvino A, D'Ambrosio D, Bianco A, Ortaggi G, Savino M. Franceschin M, et al. Among authors: savino m. Bioorg Med Chem Lett. 2007 May 1;17(9):2515-22. doi: 10.1016/j.bmcl.2007.02.021. Epub 2007 Feb 9. Bioorg Med Chem Lett. 2007. PMID: 17317176

4

The number and distances of positive charges of polyamine side chains in a series of perylene diimides significantly influence their ability to induce G-quadruplex structures and inhibit human telomerase.

Franceschin M, Lombardo CM, Pascucci E, D'Ambrosio D, Micheli E, Bianco A, Ortaggi G, Savino M. Franceschin M, et al. Among authors: savino m. Bioorg Med Chem. 2008 Mar 1;16(5):2292-304. doi: 10.1016/j.bmc.2007.11.065. Epub 2007 Nov 29. Bioorg Med Chem. 2008. PMID: 18165014

5

Selective G-quadruplex ligands: the significant role of side chain charge density in a series of perylene derivatives.

Micheli E, Lombardo CM, D'Ambrosio D, Franceschin M, Neidle S, Savino M. Micheli E, et al. Among authors: savino m. Bioorg Med Chem Lett. 2009 Jul 15;19(14):3903-8. doi: 10.1016/j.bmcl.2009.03.106. Epub 2009 Mar 26. Bioorg Med Chem Lett. 2009. PMID: 19376705

6

Self-organization of G-quadruplex structures in the hTERT core promoter stabilized by polyaminic side chain perylene derivatives.

Micheli E, Martufi M, Cacchione S, De Santis P, Savino M. Micheli E, et al. Among authors: savino m. Biophys Chem. 2010 Dec;153(1):43-53. doi: 10.1016/j.bpc.2010.10.003. Epub 2010 Oct 13. Biophys Chem. 2010. PMID: 21036459

7

Perylene diimides with different side chains are selective in inducing different G-quadruplex DNA structures and in inhibiting telomerase.

Rossetti L, Franceschin M, Bianco A, Ortaggi G, Savino M. Rossetti L, et al. Among authors: savino m. Bioorg Med Chem Lett. 2002 Sep 16;12(18):2527-33. doi: 10.1016/s0960-894x(02)00504-8. Bioorg Med Chem Lett. 2002. PMID: 12182853

8

Selective interactions of perylene derivatives having different side chains with inter- and intramolecular G-quadruplex DNA structures. A correlation with telomerase inhibition.

Rossetti L, Franceschin M, Schirripa S, Bianco A, Ortaggi G, Savino M. Rossetti L, et al. Among authors: savino m. Bioorg Med Chem Lett. 2005 Jan 17;15(2):413-20. doi: 10.1016/j.bmcl.2004.10.061. Bioorg Med Chem Lett. 2005. PMID: 15603964

9

Natural and synthetic G-quadruplex interactive berberine derivatives.

Franceschin M, Rossetti L, D'Ambrosio A, Schirripa S, Bianco A, Ortaggi G, Savino M, Schultes C, Neidle S. Franceschin M, et al. Among authors: savino m. Bioorg Med Chem Lett. 2006 Mar 15;16(6):1707-11. doi: 10.1016/j.bmcl.2005.12.001. Epub 2006 Jan 11. Bioorg Med Chem Lett. 2006. PMID: 16377184

10

Specific binding of telomeric G-quadruplexes by hydrosoluble perylene derivatives inhibits repeat addition processivity of human telomerase.

D'Ambrosio D, Reichenbach P, Micheli E, Alvino A, Franceschin M, Savino M, Lingner J. D'Ambrosio D, et al. Among authors: savino m. Biochimie. 2012 Mar;94(3):854-63. doi: 10.1016/j.biochi.2011.12.004. Epub 2011 Dec 9. Biochimie. 2012. PMID: 22182489

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