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A CD1d-dependent antagonist inhibits the activation of invariant NKT cells and prevents development of allergen-induced airway hyperreactivity.
Lombardi V, Stock P, Singh AK, Kerzerho J, Yang W, Sullivan BA, Li X, Shiratsuchi T, Hnatiuk NE, Howell AR, Yu KO, Porcelli SA, Tsuji M, Kronenberg M, Wilson SB, Akbari O. Lombardi V, et al. Among authors: porcelli sa. J Immunol. 2010 Feb 15;184(4):2107-15. doi: 10.4049/jimmunol.0901208. Epub 2010 Jan 18. J Immunol. 2010. PMID: 20083656 Free PMC article.
A Novel Glycolipid Antigen for NKT Cells That Preferentially Induces IFN-γ Production.
Birkholz AM, Girardi E, Wingender G, Khurana A, Wang J, Zhao M, Zahner S, Illarionov PA, Wen X, Li M, Yuan W, Porcelli SA, Besra GS, Zajonc DM, Kronenberg M. Birkholz AM, et al. Among authors: porcelli sa. J Immunol. 2015 Aug 1;195(3):924-33. doi: 10.4049/jimmunol.1500070. Epub 2015 Jun 15. J Immunol. 2015. PMID: 26078271 Free PMC article.
A Subset of CD8αβ+ Invariant NKT Cells in a Humanized Mouse Model.
Wen X, Kim S, Xiong R, Li M, Lawrenczyk A, Huang X, Chen SY, Rao P, Besra GS, Dellabona P, Casorati G, Porcelli SA, Akbari O, Exley MA, Yuan W. Wen X, et al. Among authors: porcelli sa. J Immunol. 2015 Aug 15;195(4):1459-69. doi: 10.4049/jimmunol.1500574. Epub 2015 Jul 8. J Immunol. 2015. PMID: 26157173 Free PMC article.
The T cell antigen receptor expressed by Valpha14i NKT cells has a unique mode of glycosphingolipid antigen recognition.
Sidobre S, Hammond KJ, Bénazet-Sidobre L, Maltsev SD, Richardson SK, Ndonye RM, Howell AR, Sakai T, Besra GS, Porcelli SA, Kronenberg M. Sidobre S, et al. Among authors: porcelli sa. Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12254-9. doi: 10.1073/pnas.0404632101. Epub 2004 Aug 10. Proc Natl Acad Sci U S A. 2004. PMID: 15304644 Free PMC article.
Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands.
Florence WC, Xia C, Gordy LE, Chen W, Zhang Y, Scott-Browne J, Kinjo Y, Yu KO, Keshipeddy S, Pellicci DG, Patel O, Kjer-Nielsen L, McCluskey J, Godfrey DI, Rossjohn J, Richardson SK, Porcelli SA, Howell AR, Hayakawa K, Gapin L, Zajonc DM, Wang PG, Joyce S. Florence WC, et al. Among authors: porcelli sa. EMBO J. 2009 Nov 18;28(22):3579-90. doi: 10.1038/emboj.2009.286. Epub 2009 Oct 8. EMBO J. 2009. PMID: 19816402 Free PMC article.
Glycolipids that elicit IFN-γ-biased responses from natural killer T cells.
Tyznik AJ, Farber E, Girardi E, Birkholz A, Li Y, Chitale S, So R, Arora P, Khurana A, Wang J, Porcelli SA, Zajonc DM, Kronenberg M, Howell AR. Tyznik AJ, et al. Among authors: porcelli sa. Chem Biol. 2011 Dec 23;18(12):1620-30. doi: 10.1016/j.chembiol.2011.10.015. Chem Biol. 2011. PMID: 22195564 Free PMC article.
287 results