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Identification and characterization of the first small molecule inhibitor of MDMX.
Reed D, Shen Y, Shelat AA, Arnold LA, Ferreira AM, Zhu F, Mills N, Smithson DC, Regni CA, Bashford D, Cicero SA, Schulman BA, Jochemsen AG, Guy RK, Dyer MA. Reed D, et al. Among authors: dyer ma. J Biol Chem. 2010 Apr 2;285(14):10786-96. doi: 10.1074/jbc.M109.056747. Epub 2010 Jan 15. J Biol Chem. 2010. PMID: 20080970 Free PMC article.
Inactivation of the p53 pathway in retinoblastoma.
Laurie NA, Donovan SL, Shih CS, Zhang J, Mills N, Fuller C, Teunisse A, Lam S, Ramos Y, Mohan A, Johnson D, Wilson M, Rodriguez-Galindo C, Quarto M, Francoz S, Mendrysa SM, Guy RK, Marine JC, Jochemsen AG, Dyer MA. Laurie NA, et al. Among authors: dyer ma. Nature. 2006 Nov 2;444(7115):61-6. doi: 10.1038/nature05194. Nature. 2006. PMID: 17080083
MDMX: from bench to bedside.
Marine JC, Dyer MA, Jochemsen AG. Marine JC, et al. Among authors: dyer ma. J Cell Sci. 2007 Feb 1;120(Pt 3):371-8. doi: 10.1242/jcs.03362. J Cell Sci. 2007. PMID: 17251377 Review.
Targeting MDM2 and MDMX in retinoblastoma.
Laurie NA, Shih CS, Dyer MA. Laurie NA, et al. Among authors: dyer ma. Curr Cancer Drug Targets. 2007 Nov;7(7):689-95. doi: 10.2174/156800907782418266. Curr Cancer Drug Targets. 2007. PMID: 18045074 Review.
Changes in retinoblastoma cell adhesion associated with optic nerve invasion.
Laurie N, Mohan A, McEvoy J, Reed D, Zhang J, Schweers B, Ajioka I, Valentine V, Johnson D, Ellison D, Dyer MA. Laurie N, et al. Among authors: dyer ma. Mol Cell Biol. 2009 Dec;29(23):6268-82. doi: 10.1128/MCB.00374-09. Epub 2009 Sep 28. Mol Cell Biol. 2009. PMID: 19786571 Free PMC article.
Whole-body physiologically based pharmacokinetic model for nutlin-3a in mice after intravenous and oral administration.
Zhang F, Tagen M, Throm S, Mallari J, Miller L, Guy RK, Dyer MA, Williams RT, Roussel MF, Nemeth K, Zhu F, Zhang J, Lu M, Panetta JC, Boulos N, Stewart CF. Zhang F, et al. Among authors: dyer ma. Drug Metab Dispos. 2011 Jan;39(1):15-21. doi: 10.1124/dmd.110.035915. Epub 2010 Oct 14. Drug Metab Dispos. 2011. PMID: 20947617 Free PMC article.
Targeting the p53 pathway in retinoblastoma with subconjunctival Nutlin-3a.
Brennan RC, Federico S, Bradley C, Zhang J, Flores-Otero J, Wilson M, Stewart C, Zhu F, Guy K, Dyer MA. Brennan RC, et al. Among authors: dyer ma. Cancer Res. 2011 Jun 15;71(12):4205-13. doi: 10.1158/0008-5472.CAN-11-0058. Epub 2011 Apr 22. Cancer Res. 2011. PMID: 21515735 Free PMC article.
194 results