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Alzheimer's disease and the amyloid-beta peptide.
Murphy MP, LeVine H 3rd. Murphy MP, et al. J Alzheimers Dis. 2010;19(1):311-23. doi: 10.3233/JAD-2010-1221. J Alzheimers Dis. 2010. PMID: 20061647 Free PMC article. Review.
Testing the neurovascular hypothesis of Alzheimer's disease: LRP-1 antisense reduces blood-brain barrier clearance, increases brain levels of amyloid-beta protein, and impairs cognition.
Jaeger LB, Dohgu S, Hwang MC, Farr SA, Murphy MP, Fleegal-DeMotta MA, Lynch JL, Robinson SM, Niehoff ML, Johnson SN, Kumar VB, Banks WA. Jaeger LB, et al. Among authors: murphy mp. J Alzheimers Dis. 2009;17(3):553-70. doi: 10.3233/JAD-2009-1074. J Alzheimers Dis. 2009. PMID: 19433890 Free PMC article.
BACE1 and BACE2 enzymatic activities in Alzheimer's disease.
Ahmed RR, Holler CJ, Webb RL, Li F, Beckett TL, Murphy MP. Ahmed RR, et al. Among authors: murphy mp. J Neurochem. 2010 Feb;112(4):1045-53. doi: 10.1111/j.1471-4159.2009.06528.x. Epub 2009 Dec 4. J Neurochem. 2010. PMID: 19968762 Free PMC article.
795 results