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Selective cleavage and anticoagulant activity of a sulfated fucan: stereospecific removal of a 2-sulfate ester from the polysaccharide by mild acid hydrolysis, preparation of oligosaccharides, and heparin cofactor II-dependent anticoagulant activity.
Pomin VH, Pereira MS, Valente AP, Tollefsen DM, Pavão MS, Mourão PA. Pomin VH, et al. Among authors: pavao ms. Glycobiology. 2005 Apr;15(4):369-81. doi: 10.1093/glycob/cwi021. Epub 2004 Dec 8. Glycobiology. 2005. PMID: 15590773
The Hemolymph of the ascidian Styela plicata (Chordata-Tunicata) contains heparin inside basophil-like cells and a unique sulfated galactoglucan in the plasma.
de Barros CM, Andrade LR, Allodi S, Viskov C, Mourier PA, Cavalcante MC, Straus AH, Takahashi HK, Pomin VH, Carvalho VF, Martins MA, Pavão MS. de Barros CM, et al. Among authors: pavao ms. J Biol Chem. 2007 Jan 19;282(3):1615-26. doi: 10.1074/jbc.M604056200. Epub 2006 Nov 17. J Biol Chem. 2007. PMID: 17114184 Free article.
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