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Page 1
Extended blood stage sensitivity profiles of Plasmodium cynomolgi to doxycycline and tafenoquine, as a model for Plasmodium vivax.
Christensen P, Cinzah R, Suwanarusk R, Chua ACY, Kaneko O, Kyle DE, Aung HL, Matheson J, Bifani P, Rénia L, Cook GM, Snounou G, Russell B. Christensen P, et al. Among authors: cook gm. Antimicrob Agents Chemother. 2024 May 2;68(5):e0028024. doi: 10.1128/aac.00280-24. Epub 2024 Apr 8. Antimicrob Agents Chemother. 2024. PMID: 38587391
Synthesis, Structure-Activity Relationship Study, Bioactivity, and Nephrotoxicity Evaluation of the Proposed Structure of the Cyclic Lipodepsipeptide Brevicidine B.
Palpal-Latoc D, Horsfall AJ, Cameron AJ, Campbell G, Ferguson SA, Cook GM, Sander V, Davidson AJ, Harris PWR, Brimble MA. Palpal-Latoc D, et al. Among authors: cook gm. J Nat Prod. 2024 Apr 26;87(4):764-773. doi: 10.1021/acs.jnatprod.3c00876. Epub 2024 Feb 29. J Nat Prod. 2024. PMID: 38423998
A dual-targeting succinate dehydrogenase and F1Fo-ATP synthase inhibitor rapidly sterilizes replicating and non-replicating Mycobacterium tuberculosis.
Adolph C, Cheung CY, McNeil MB, Jowsey WJ, Williams ZC, Hards K, Harold LK, Aboelela A, Bujaroski RS, Buckley BJ, Tyndall JDA, Li Z, Langer JD, Preiss L, Meier T, Steyn AJC, Rhee KY, Berney M, Kelso MJ, Cook GM. Adolph C, et al. Among authors: cook gm. Cell Chem Biol. 2024 Apr 18;31(4):683-698.e7. doi: 10.1016/j.chembiol.2023.12.002. Epub 2023 Dec 26. Cell Chem Biol. 2024. PMID: 38151019
Structural basis for bacterial energy extraction from atmospheric hydrogen.
Grinter R, Kropp A, Venugopal H, Senger M, Badley J, Cabotaje PR, Jia R, Duan Z, Huang P, Stripp ST, Barlow CK, Belousoff M, Shafaat HS, Cook GM, Schittenhelm RB, Vincent KA, Khalid S, Berggren G, Greening C. Grinter R, et al. Among authors: cook gm. Nature. 2023 Mar;615(7952):541-547. doi: 10.1038/s41586-023-05781-7. Epub 2023 Mar 8. Nature. 2023. PMID: 36890228 Free PMC article.
Synthesis, Antibacterial Activity, and Nephrotoxicity of Polymyxin B Analogues Modified at Leu-7, d-Phe-6, and the N-Terminus Enabled by S-Lipidation.
Harris PWR, Siow A, Yang SH, Wadsworth AD, Tan L, Hermant Y, Mao Y, An C, Hanna CC, Cameron AJ, Allison JR, Chakraborty A, Ferguson SA, Mros S, Hards K, Cook GM, Williamson DA, Carter GP, Chan STS, Painter GA, Sander V, Davidson AJ, Brimble MA. Harris PWR, et al. Among authors: cook gm. ACS Infect Dis. 2022 Dec 9;8(12):2413-2429. doi: 10.1021/acsinfecdis.1c00347. Epub 2022 Nov 22. ACS Infect Dis. 2022. PMID: 36413173
330 results