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Structure-activity relationship and mechanism of action studies of manzamine analogues for the control of neuroinflammation and cerebral infections.
Peng J, Kudrimoti S, Prasanna S, Odde S, Doerksen RJ, Pennaka HK, Choo YM, Rao KV, Tekwani BL, Madgula V, Khan SI, Wang B, Mayer AM, Jacob MR, Tu LC, Gertsch J, Hamann MT. Peng J, et al. Among authors: madgula v. J Med Chem. 2010 Jan 14;53(1):61-76. doi: 10.1021/jm900672t. J Med Chem. 2010. PMID: 20017491 Free PMC article.
Discovery and evaluation of novel FAAH inhibitors in neuropathic pain model.
Bhuniya D, Kharul RK, Hajare A, Shaikh N, Bhosale S, Balwe S, Begum F, De S, Athavankar S, Joshi D, Madgula V, Joshi K, Raje AA, Meru AV, Magdum A, Mookhtiar KA, Barbhaiya R. Bhuniya D, et al. Among authors: madgula v. Bioorg Med Chem Lett. 2019 Jan 15;29(2):238-243. doi: 10.1016/j.bmcl.2018.11.048. Epub 2018 Nov 24. Bioorg Med Chem Lett. 2019. PMID: 30503633
Discovery of Potent and Selective A2A Antagonists with Efficacy in Animal Models of Parkinson's Disease and Depression.
Basu S, Barawkar DA, Ramdas V, Naykodi M, Shejul YD, Patel M, Thorat S, Panmand A, Kashinath K, Bonagiri R, Prasad V, Bhat G, Quraishi A, Chaudhary S, Magdum A, Meru AV, Ghosh I, Bhamidipati RK, Raje AA, Madgula VLM, De S, Rouduri SR, Palle VP, Chugh A, Hariharan N, Mookhtiar KA. Basu S, et al. Among authors: madgula vlm. ACS Med Chem Lett. 2017 Jul 5;8(8):835-840. doi: 10.1021/acsmedchemlett.7b00175. eCollection 2017 Aug 10. ACS Med Chem Lett. 2017. PMID: 28835798 Free PMC article.
Discovery of liver-directed glucokinase activator having anti-hyperglycemic effect without hypoglycemia.
Deshpande AM, Bhuniya D, De S, Dave B, Vyavahare VP, Kurhade SH, Kandalkar SR, Naik KP, Kobal BS, Kaduskar RD, Basu S, Jain V, Patil P, Chaturvedi Joshi S, Bhat G, Raje AA, Reddy S, Gundu J, Madgula V, Tambe S, Shitole P, Umrani D, Chugh A, Palle VP, Mookhtiar KA. Deshpande AM, et al. Among authors: madgula v. Eur J Med Chem. 2017 Jun 16;133:268-286. doi: 10.1016/j.ejmech.2017.03.042. Epub 2017 Mar 24. Eur J Med Chem. 2017. PMID: 28390958
Discovery and evaluation of 1H-pyrrolo[2,3-b]pyridine based selective and reversible small molecule BTK inhibitors for the treatment of rheumatoid arthritis.
Thakkar M, Bhuniya D, Kaduskar R, Mengawade T, Naik K, Salunkhe V, Bhalerao A, Kurhade S, Mavinahalli J, Jain V, Petla R, Avaragolla S, Ray S, Rouduri S, Dhanave A, De S, Pathade V, Tambe A, Raje AA, Madgula V, Joshi S, Nadeem A, Bala M, Umrani D, Hariharan N, Kulkarni B, Mookhtiar KA. Thakkar M, et al. Among authors: madgula v. Bioorg Med Chem Lett. 2017 Apr 15;27(8):1867-1873. doi: 10.1016/j.bmcl.2017.02.026. Epub 2017 Feb 22. Bioorg Med Chem Lett. 2017. PMID: 28279528
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