Lane DP - Search Results

1

Awakening guardian angels: drugging the p53 pathway.

Brown CJ, Lain S, Verma CS, Fersht AR, Lane DP. Brown CJ, et al. Among authors: lane dp. Nat Rev Cancer. 2009 Dec;9(12):862-73. doi: 10.1038/nrc2763. Nat Rev Cancer. 2009. PMID: 19935675 Review.

2

Inhibition of pRb phosphorylation and cell-cycle progression by a 20-residue peptide derived from p16CDKN2/INK4A.

Fåhraeus R, Paramio JM, Ball KL, Laín S, Lane DP. Fåhraeus R, et al. Among authors: lane dp. Curr Biol. 1996 Jan 1;6(1):84-91. doi: 10.1016/s0960-9822(02)00425-6. Curr Biol. 1996. PMID: 8805225 Free article.

3

Cell-cycle arrest and inhibition of Cdk4 activity by small peptides based on the carboxy-terminal domain of p21WAF1.

Ball KL, Lain S, Fâhraeus R, Smythe C, Lane DP. Ball KL, et al. Among authors: lane dp. Curr Biol. 1997 Jan 1;7(1):71-80. doi: 10.1016/s0960-9822(06)00029-7. Curr Biol. 1997. PMID: 8999999 Free article.

4

Thermodynamic stability of wild-type and mutant p53 core domain.

Bullock AN, Henckel J, DeDecker BS, Johnson CM, Nikolova PV, Proctor MR, Lane DP, Fersht AR. Bullock AN, et al. Among authors: lane dp. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14338-42. doi: 10.1073/pnas.94.26.14338. Proc Natl Acad Sci U S A. 1997. PMID: 9405613 Free PMC article.

5

Characterization of the cyclin-dependent kinase inhibitory domain of the INK4 family as a model for a synthetic tumour suppressor molecule.

Fåhraeus R, Laín S, Ball KL, Lane DP. Fåhraeus R, et al. Among authors: lane dp. Oncogene. 1998 Feb 5;16(5):587-96. doi: 10.1038/sj.onc.1201580. Oncogene. 1998. PMID: 9482104

6

Semirational design of active tumor suppressor p53 DNA binding domain with enhanced stability.

Nikolova PV, Henckel J, Lane DP, Fersht AR. Nikolova PV, et al. Among authors: lane dp. Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):14675-80. doi: 10.1073/pnas.95.25.14675. Proc Natl Acad Sci U S A. 1998. PMID: 9843948 Free PMC article.

7

An inhibitor of nuclear export activates the p53 response and induces the localization of HDM2 and p53 to U1A-positive nuclear bodies associated with the PODs.

Laín S, Midgley C, Sparks A, Lane EB, Lane DP. Laín S, et al. Among authors: lane eb, lane dp. Exp Cell Res. 1999 May 1;248(2):457-72. doi: 10.1006/excr.1999.4433. Exp Cell Res. 1999. PMID: 10222137

8

SUMO-1 modification activates the transcriptional response of p53.

Rodriguez MS, Desterro JM, Lain S, Midgley CA, Lane DP, Hay RT. Rodriguez MS, et al. Among authors: lane dp. EMBO J. 1999 Nov 15;18(22):6455-61. doi: 10.1093/emboj/18.22.6455. EMBO J. 1999. PMID: 10562557 Free PMC article.

9

Accumulating active p53 in the nucleus by inhibition of nuclear export: a novel strategy to promote the p53 tumor suppressor function.

Laín S, Xirodimas D, Lane DP. Laín S, et al. Among authors: lane dp. Exp Cell Res. 1999 Dec 15;253(2):315-24. doi: 10.1006/excr.1999.4672. Exp Cell Res. 1999. PMID: 10585254 Review. No abstract available.

10

Effects on normal fibroblasts and neuroblastoma cells of the activation of the p53 response by the nuclear export inhibitor leptomycin B.

Smart P, Lane EB, Lane DP, Midgley C, Vojtesek B, Laín S. Smart P, et al. Among authors: lane eb, lane dp. Oncogene. 1999 Dec 2;18(51):7378-86. doi: 10.1038/sj.onc.1203260. Oncogene. 1999. PMID: 10602494

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