Delaine T - Search Results

1

Synthesis and antitumor evaluation of analogues of the marine pyrroloiminoquinone tsitsikammamines.

Rives A, Le Calvé B, Delaine T, Legentil L, Kiss R, Delfourne E. Rives A, et al. Among authors: delaine t. Eur J Med Chem. 2010 Jan;45(1):343-51. doi: 10.1016/j.ejmech.2009.10.019. Epub 2009 Oct 14. Eur J Med Chem. 2010. PMID: 19897281

2

Galectin-inhibitory thiodigalactoside ester derivatives have antimigratory effects in cultured lung and prostate cancer cells.

Delaine T, Cumpstey I, Ingrassia L, Le Mercier M, Okechukwu P, Leffler H, Kiss R, Nilsson UJ. Delaine T, et al. J Med Chem. 2008 Dec 25;51(24):8109-14. doi: 10.1021/jm801077j. J Med Chem. 2008. PMID: 19053747

3

Development of isoniazid-NAD truncated adducts embedding a lipophilic fragment as potential bi-substrate InhA inhibitors and antimycobacterial agents.

Delaine T, Bernardes-Génisson V, Quémard A, Constant P, Meunier B, Bernadou J. Delaine T, et al. Eur J Med Chem. 2010 Oct;45(10):4554-61. doi: 10.1016/j.ejmech.2010.07.016. Epub 2010 Jul 15. Eur J Med Chem. 2010. PMID: 20696503

4

Synthesis of the isonicotinoylnicotinamide scaffolds of the naturally occurring isoniazid-NAD(P) adducts.

Delaine T, Bernardes-Génisson V, Meunier B, Bernadou J. Delaine T, et al. J Org Chem. 2007 Jan 19;72(2):675-8. doi: 10.1021/jo062100e. J Org Chem. 2007. PMID: 17221997

5

Preliminary investigations of the effect of lipophilic analogues of the active metabolite of isoniazid toward bacterial and plasmodial strains.

Delaine T, Bernardes-Génisson V, Quémard A, Constant P, Cosledan F, Meunier B, Bernadou J. Delaine T, et al. Chem Biol Drug Des. 2012 Jun;79(6):1001-6. doi: 10.1111/j.1747-0285.2012.01374.x. Epub 2012 Apr 10. Chem Biol Drug Des. 2012. PMID: 22405039

6

Galectin-3-Binding Glycomimetics that Strongly Reduce Bleomycin-Induced Lung Fibrosis and Modulate Intracellular Glycan Recognition.

Delaine T, Collins P, MacKinnon A, Sharma G, Stegmayr J, Rajput VK, Mandal S, Cumpstey I, Larumbe A, Salameh BA, Kahl-Knutsson B, van Hattum H, van Scherpenzeel M, Pieters RJ, Sethi T, Schambye H, Oredsson S, Leffler H, Blanchard H, Nilsson UJ. Delaine T, et al. Chembiochem. 2016 Sep 15;17(18):1759-70. doi: 10.1002/cbic.201600285. Epub 2016 Aug 12. Chembiochem. 2016. PMID: 27356186 Free article.

7

Protein flexibility and conformational entropy in ligand design targeting the carbohydrate recognition domain of galectin-3.

Diehl C, Engström O, Delaine T, Håkansson M, Genheden S, Modig K, Leffler H, Ryde U, Nilsson UJ, Akke M. Diehl C, et al. Among authors: delaine t. J Am Chem Soc. 2010 Oct 20;132(41):14577-89. doi: 10.1021/ja105852y. J Am Chem Soc. 2010. PMID: 20873837 Free PMC article.

8

Synthesis of 3-azido-3-deoxy-beta-D-galactopyranosides.

Oberg CT, Noresson AL, Delaine T, Larumbe A, Tejler J, von Wachenfeldt H, Nilsson UJ. Oberg CT, et al. Among authors: delaine t. Carbohydr Res. 2009 Jul 27;344(11):1282-4. doi: 10.1016/j.carres.2009.05.005. Epub 2009 May 9. Carbohydr Res. 2009. PMID: 19505681

9

Galectin-3 targeted therapy with a small molecule inhibitor activates apoptosis and enhances both chemosensitivity and radiosensitivity in papillary thyroid cancer.

Lin CI, Whang EE, Donner DB, Jiang X, Price BD, Carothers AM, Delaine T, Leffler H, Nilsson UJ, Nose V, Moore FD Jr, Ruan DT. Lin CI, et al. Among authors: delaine t. Mol Cancer Res. 2009 Oct;7(10):1655-62. doi: 10.1158/1541-7786.MCR-09-0274. Epub 2009 Oct 13. Mol Cancer Res. 2009. PMID: 19825987

10

Regulation of transforming growth factor-β1-driven lung fibrosis by galectin-3.

Mackinnon AC, Gibbons MA, Farnworth SL, Leffler H, Nilsson UJ, Delaine T, Simpson AJ, Forbes SJ, Hirani N, Gauldie J, Sethi T. Mackinnon AC, et al. Among authors: delaine t. Am J Respir Crit Care Med. 2012 Mar 1;185(5):537-46. doi: 10.1164/rccm.201106-0965OC. Epub 2011 Nov 17. Am J Respir Crit Care Med. 2012. PMID: 22095546 Free PMC article.

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