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Dopaminergic drug treatment remediates exaggerated cingulate prediction error responses in obsessive-compulsive disorder.
Murray GK, Knolle F, Ersche KD, Craig KJ, Abbott S, Shabbir SS, Fineberg NA, Suckling J, Sahakian BJ, Bullmore ET, Robbins TW. Murray GK, et al. Among authors: shabbir ss. Psychopharmacology (Berl). 2019 Aug;236(8):2325-2336. doi: 10.1007/s00213-019-05292-2. Epub 2019 Jun 14. Psychopharmacology (Berl). 2019. PMID: 31201476 Free PMC article. Clinical Trial.
Response perseveration in stimulant dependence is associated with striatal dysfunction and can be ameliorated by a D(2/3) receptor agonist.
Ersche KD, Roiser JP, Abbott S, Craig KJ, Müller U, Suckling J, Ooi C, Shabbir SS, Clark L, Sahakian BJ, Fineberg NA, Merlo-Pich EV, Robbins TW, Bullmore ET. Ersche KD, et al. Among authors: shabbir ss. Biol Psychiatry. 2011 Oct 15;70(8):754-762. doi: 10.1016/j.biopsych.2011.06.033. Biol Psychiatry. 2011. PMID: 21967987 Clinical Trial.
The discovery of GSK221149A: a potent and selective oxytocin antagonist.
Liddle J, Allen MJ, Borthwick AD, Brooks DP, Davies DE, Edwards RM, Exall AM, Hamlett C, Irving WR, Mason AM, McCafferty GP, Nerozzi F, Peace S, Philp J, Pollard D, Pullen MA, Shabbir SS, Sollis SL, Westfall TD, Woollard PM, Wu C, Hickey DM. Liddle J, et al. Among authors: shabbir ss. Bioorg Med Chem Lett. 2008 Jan 1;18(1):90-4. doi: 10.1016/j.bmcl.2007.11.008. Epub 2007 Nov 6. Bioorg Med Chem Lett. 2008. PMID: 18032036