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chi-Conopeptide pharmacophore development: toward a novel class of norepinephrine transporter inhibitor (Xen2174) for pain.
J Med Chem. 2009 Nov 26;52(22):6991-7002. doi: 10.1021/jm9003413.
J Med Chem. 2009.
PMID: 19860431
Allosteric alpha 1-adrenoreceptor antagonism by the conopeptide rho-TIA.
Sharpe IA, Thomas L, Loughnan M, Motin L, Palant E, Croker DE, Alewood D, Chen S, Graham RM, Alewood PF, Adams DJ, Lewis RJ.
Sharpe IA, et al. Among authors: palant e.
J Biol Chem. 2003 Sep 5;278(36):34451-7. doi: 10.1074/jbc.M305410200. Epub 2003 Jun 24.
J Biol Chem. 2003.
PMID: 12824165
Free article.
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Inhibition of the norepinephrine transporter by the venom peptide chi-MrIA. Site of action, Na+ dependence, and structure-activity relationship.
Sharpe IA, Palant E, Schroeder CI, Kaye DM, Adams DJ, Alewood PF, Lewis RJ.
Sharpe IA, et al. Among authors: palant e.
J Biol Chem. 2003 Oct 10;278(41):40317-23. doi: 10.1074/jbc.M213030200. Epub 2003 Jul 28.
J Biol Chem. 2003.
PMID: 12885787
Free article.
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Anti-allodynic efficacy of the chi-conopeptide, Xen2174, in rats with neuropathic pain.
Nielsen CK, Lewis RJ, Alewood D, Drinkwater R, Palant E, Patterson M, Yaksh TL, McCumber D, Smith MT.
Nielsen CK, et al. Among authors: palant e.
Pain. 2005 Nov;118(1-2):112-24. doi: 10.1016/j.pain.2005.08.002. Epub 2005 Sep 9.
Pain. 2005.
PMID: 16154696
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Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter.
Sharpe IA, Gehrmann J, Loughnan ML, Thomas L, Adams DA, Atkins A, Palant E, Craik DJ, Adams DJ, Alewood PF, Lewis RJ.
Sharpe IA, et al. Among authors: palant e.
Nat Neurosci. 2001 Sep;4(9):902-7. doi: 10.1038/nn0901-902.
Nat Neurosci. 2001.
PMID: 11528421
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Crystallization of PNMT, the adrenaline-synthesizing enzyme, is critically dependent on a high protein concentration.
Begun J, McLeish MJ, Caine JM, Palant E, Grunewald GL, Martin JL.
Begun J, et al. Among authors: palant e.
Acta Crystallogr D Biol Crystallogr. 2002 Feb;58(Pt 2):314-5. doi: 10.1107/s090744490101962x. Epub 2002 Jan 24.
Acta Crystallogr D Biol Crystallogr. 2002.
PMID: 11807261
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A rapid, semi-automated method for detection of Galbeta1-4GlcNAc alpha2,6-sialyltransferase (EC 2.4.99.1) activity using the lectin Sambucus nigra agglutinin.
Halliday JA, Franks AH, Ramsdale TE, Martin R, Palant E.
Halliday JA, et al. Among authors: palant e.
Glycobiology. 2001 Jul;11(7):557-64. doi: 10.1093/glycob/11.7.557.
Glycobiology. 2001.
PMID: 11447135
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