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A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
Landi MT, Chatterjee N, Yu K, Goldin LR, Goldstein AM, Rotunno M, Mirabello L, Jacobs K, Wheeler W, Yeager M, Bergen AW, Li Q, Consonni D, Pesatori AC, Wacholder S, Thun M, Diver R, Oken M, Virtamo J, Albanes D, Wang Z, Burdette L, Doheny KF, Pugh EW, Laurie C, Brennan P, Hung R, Gaborieau V, McKay JD, Lathrop M, McLaughlin J, Wang Y, Tsao MS, Spitz MR, Wang Y, Krokan H, Vatten L, Skorpen F, Arnesen E, Benhamou S, Bouchard C, Metspalu A, Metsapalu A, Vooder T, Nelis M, Välk K, Field JK, Chen C, Goodman G, Sulem P, Thorleifsson G, Rafnar T, Eisen T, Sauter W, Rosenberger A, Bickeböller H, Risch A, Chang-Claude J, Wichmann HE, Stefansson K, Houlston R, Amos CI, Fraumeni JF Jr, Savage SA, Bertazzi PA, Tucker MA, Chanock S, Caporaso NE. Landi MT, et al. Among authors: houlston r. Am J Hum Genet. 2009 Nov;85(5):679-91. doi: 10.1016/j.ajhg.2009.09.012. Epub 2009 Oct 15. Am J Hum Genet. 2009. PMID: 19836008 Free PMC article.
Variation in the CTLA4/CD28 gene region confers an increased risk of coeliac disease.
Popat S, Hearle N, Hogberg L, Braegger CP, O'Donoghue D, Falth-Magnusson K, Holmes GK, Howdle PD, Jenkins H, Johnston S, Kennedy NP, Kumar PJ, Logan RF, Marsh MN, Mulder CJ, Torinsson Naluai A, Sjoberg K, Stenhammar L, Walters JR, Jewell DP, Houlston RS. Popat S, et al. Among authors: houlston rs. Ann Hum Genet. 2002 Mar;66(Pt 2):125-37. doi: 10.1017/S0003480002001021. Ann Hum Genet. 2002. PMID: 12174216 Review.
Diagnostic criteria for monoclonal B-cell lymphocytosis.
Marti GE, Rawstron AC, Ghia P, Hillmen P, Houlston RS, Kay N, Schleinitz TA, Caporaso N; International Familial CLL Consortium. Marti GE, et al. Br J Haematol. 2005 Aug;130(3):325-32. doi: 10.1111/j.1365-2141.2005.05550.x. Br J Haematol. 2005. PMID: 16042682 Free article. Review.
Evidence for a colorectal cancer susceptibility locus on chromosome 3q21-q24 from a high-density SNP genome-wide linkage scan.
Kemp Z, Carvajal-Carmona L, Spain S, Barclay E, Gorman M, Martin L, Jaeger E, Brooks N, Bishop DT, Thomas H, Tomlinson I, Papaemmanuil E, Webb E, Sellick GS, Wood W, Evans G, Lucassen A, Maher ER, Houlston RS; ColoRectal tumour Gene Identification (CoRGI) Study Consortium. Kemp Z, et al. Among authors: houlston rs. Hum Mol Genet. 2006 Oct 1;15(19):2903-10. doi: 10.1093/hmg/ddl231. Epub 2006 Aug 21. Hum Mol Genet. 2006. PMID: 16923799
Search for low penetrance alleles for colorectal cancer through a scan of 1467 non-synonymous SNPs in 2575 cases and 2707 controls with validation by kin-cohort analysis of 14 704 first-degree relatives.
Webb EL, Rudd MF, Sellick GS, El Galta R, Bethke L, Wood W, Fletcher O, Penegar S, Withey L, Qureshi M, Johnson N, Tomlinson I, Gray R, Peto J, Houlston RS. Webb EL, et al. Among authors: houlston rs. Hum Mol Genet. 2006 Nov 1;15(21):3263-71. doi: 10.1093/hmg/ddl401. Epub 2006 Sep 25. Hum Mol Genet. 2006. PMID: 17000706
800 results