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A Precision Therapy Approach for Retinitis Pigmentosa 11 Using Splice-Switching Antisense Oligonucleotides to Restore the Open Reading Frame of PRPF31.
Int J Mol Sci. 2024 Mar 16;25(6):3391. doi: 10.3390/ijms25063391.
Int J Mol Sci. 2024.
PMID: 38542364
Free PMC article.
DNAzymes: Expanding the Potential of Nucleic Acid Therapeutics.
Larcher LM, Pitout IL, Keegan NP, Veedu RN, Fletcher S.
Larcher LM, et al. Among authors: pitout il.
Nucleic Acid Ther. 2023 Jun;33(3):178-192. doi: 10.1089/nat.2022.0066. Epub 2023 Apr 21.
Nucleic Acid Ther. 2023.
PMID: 37093127
Free PMC article.
Review.
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Single Stranded Fully Modified-Phosphorothioate Oligonucleotides can Induce Structured Nuclear Inclusions, Alter Nuclear Protein Localization and Disturb the Transcriptome In Vitro.
Flynn LL, Li R, Pitout IL, Aung-Htut MT, Larcher LM, Cooper JAL, Greer KL, Hubbard A, Griffiths L, Bond CS, Wilton SD, Fox AH, Fletcher S.
Flynn LL, et al. Among authors: pitout il.
Front Genet. 2022 Apr 6;13:791416. doi: 10.3389/fgene.2022.791416. eCollection 2022.
Front Genet. 2022.
PMID: 35464859
Free PMC article.
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Targeted SMN Exon Skipping: A Useful Control to Assess In Vitro and In Vivo Splice-Switching Studies.
Flynn LL, Mitrpant C, Adams A, Pitout IL, Stirnweiss A, Fletcher S, Wilton SD.
Flynn LL, et al. Among authors: pitout il.
Biomedicines. 2021 May 14;9(5):552. doi: 10.3390/biomedicines9050552.
Biomedicines. 2021.
PMID: 34069072
Free PMC article.
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ALS Genetics, Mechanisms, and Therapeutics: Where Are We Now?
Mejzini R, Flynn LL, Pitout IL, Fletcher S, Wilton SD, Akkari PA.
Mejzini R, et al. Among authors: pitout il.
Front Neurosci. 2019 Dec 6;13:1310. doi: 10.3389/fnins.2019.01310. eCollection 2019.
Front Neurosci. 2019.
PMID: 31866818
Free PMC article.
Review.
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Systematic Approach to Developing Splice Modulating Antisense Oligonucleotides.
Aung-Htut MT, McIntosh CS, Ham KA, Pitout IL, Flynn LL, Greer K, Fletcher S, Wilton SD.
Aung-Htut MT, et al. Among authors: pitout il.
Int J Mol Sci. 2019 Oct 11;20(20):5030. doi: 10.3390/ijms20205030.
Int J Mol Sci. 2019.
PMID: 31614438
Free PMC article.
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Antisense Oligonucleotide-Mediated Terminal Intron Retention of the SMN2 Transcript.
Flynn LL, Mitrpant C, Pitout IL, Fletcher S, Wilton SD.
Flynn LL, et al. Among authors: pitout il.
Mol Ther Nucleic Acids. 2018 Jun 1;11:91-102. doi: 10.1016/j.omtn.2018.01.011. Epub 2018 Jan 31.
Mol Ther Nucleic Acids. 2018.
PMID: 29858094
Free PMC article.
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The effect of electromagnetic radiation in the mobile phone range on the behaviour of the rat.
Daniels WM, Pitout IL, Afullo TJ, Mabandla MV.
Daniels WM, et al. Among authors: pitout il.
Metab Brain Dis. 2009 Dec;24(4):629-41. doi: 10.1007/s11011-009-9164-3. Epub 2009 Oct 13.
Metab Brain Dis. 2009.
PMID: 19823925
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