Jayandharan GR - Search Results

1

Optimized adeno-associated virus (AAV)-protein phosphatase-5 helper viruses for efficient liver transduction by single-stranded AAV vectors: therapeutic expression of factor IX at reduced vector doses.

Jayandharan GR, Zhong L, Sack BK, Rivers AE, Li M, Li B, Herzog RW, Srivastava A. Jayandharan GR, et al. Hum Gene Ther. 2010 Mar;21(3):271-83. doi: 10.1089/hum.2009.100. Hum Gene Ther. 2010. PMID: 19788390 Free PMC article.

2

Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression.

Zhong L, Li B, Jayandharan G, Mah CS, Govindasamy L, Agbandje-McKenna M, Herzog RW, Weigel-Van Aken KA, Hobbs JA, Zolotukhin S, Muzyczka N, Srivastava A. Zhong L, et al. Virology. 2008 Nov 25;381(2):194-202. doi: 10.1016/j.virol.2008.08.027. Epub 2008 Oct 2. Virology. 2008. PMID: 18834608 Free PMC article.

3

Strategies for improving the transduction efficiency of single-stranded adeno-associated virus vectors in vitro and in vivo.

Jayandharan GR, Zhong L, Li B, Kachniarz B, Srivastava A. Jayandharan GR, et al. Gene Ther. 2008 Sep;15(18):1287-93. doi: 10.1038/gt.2008.89. Epub 2008 May 22. Gene Ther. 2008. PMID: 18496572

4

Enhanced transgene expression from recombinant single-stranded D-sequence-substituted adeno-associated virus vectors in human cell lines in vitro and in murine hepatocytes in vivo.

Ling C, Wang Y, Lu Y, Wang L, Jayandharan GR, Aslanidi GV, Li B, Cheng B, Ma W, Lentz T, Ling C, Xiao X, Samulski RJ, Muzyczka N, Srivastava A. Ling C, et al. Among authors: jayandharan gr. J Virol. 2015 Jan 15;89(2):952-61. doi: 10.1128/JVI.02581-14. Epub 2014 Oct 29. J Virol. 2015. PMID: 25355884 Free PMC article.

5

Adeno-associated virus serotype 6 capsid tyrosine-to-phenylalanine mutations improve gene transfer to skeletal muscle.

Qiao C, Zhang W, Yuan Z, Shin JH, Li J, Jayandharan GR, Zhong L, Srivastava A, Xiao X, Duan D. Qiao C, et al. Among authors: jayandharan gr. Hum Gene Ther. 2010 Oct;21(10):1343-8. doi: 10.1089/hum.2010.003. Hum Gene Ther. 2010. PMID: 20497037 Free PMC article.

6

High-efficiency transduction of fibroblasts and mesenchymal stem cells by tyrosine-mutant AAV2 vectors for their potential use in cellular therapy.

Li M, Jayandharan GR, Li B, Ling C, Ma W, Srivastava A, Zhong L. Li M, et al. Among authors: jayandharan gr. Hum Gene Ther. 2010 Nov;21(11):1527-43. doi: 10.1089/hum.2010.005. Epub 2010 Oct 6. Hum Gene Ther. 2010. PMID: 20507237 Free PMC article.

7

Human hepatocyte growth factor receptor is a cellular coreceptor for adeno-associated virus serotype 3.

Ling C, Lu Y, Kalsi JK, Jayandharan GR, Li B, Ma W, Cheng B, Gee SW, McGoogan KE, Govindasamy L, Zhong L, Agbandje-McKenna M, Srivastava A. Ling C, et al. Among authors: jayandharan gr. Hum Gene Ther. 2010 Dec;21(12):1741-7. doi: 10.1089/hum.2010.075. Hum Gene Ther. 2010. PMID: 20545554 Free PMC article.

8

High-efficiency transduction and correction of murine hemophilia B using AAV2 vectors devoid of multiple surface-exposed tyrosines.

Markusic DM, Herzog RW, Aslanidi GV, Hoffman BE, Li B, Li M, Jayandharan GR, Ling C, Zolotukhin I, Ma W, Zolotukhin S, Srivastava A, Zhong L. Markusic DM, et al. Among authors: jayandharan gr. Mol Ther. 2010 Dec;18(12):2048-56. doi: 10.1038/mt.2010.172. Epub 2010 Aug 24. Mol Ther. 2010. PMID: 20736929 Free PMC article.

9

Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina.

Petrs-Silva H, Dinculescu A, Li Q, Deng WT, Pang JJ, Min SH, Chiodo V, Neeley AW, Govindasamy L, Bennett A, Agbandje-McKenna M, Zhong L, Li B, Jayandharan GR, Srivastava A, Lewin AS, Hauswirth WW. Petrs-Silva H, et al. Among authors: jayandharan gr. Mol Ther. 2011 Feb;19(2):293-301. doi: 10.1038/mt.2010.234. Epub 2010 Nov 2. Mol Ther. 2011. PMID: 21045809 Free PMC article.

10

A simple method to increase the transduction efficiency of single-stranded adeno-associated virus vectors in vitro and in vivo.

Ma W, Li B, Ling C, Jayandharan GR, Srivastava A, Byrne BJ. Ma W, et al. Among authors: jayandharan gr. Hum Gene Ther. 2011 May;22(5):633-40. doi: 10.1089/hum.2010.243. Hum Gene Ther. 2011. PMID: 21219084 Free PMC article.

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